Resumo
Introdução: A vitamina D tem efeitos benéficos que supostamente contribuem para a manutenção da função músculo-esquelética.
Objetivo: Analisar em uma população não selecionada o efeito dos níveis de calcidiol na função muscular de ambas as mãos, nas atividades da vida diária e nas alterações na densidade mineral óssea (DMO).
Material e métodos: Utilizou-se a coorte do estudo EVOS, que realizou, entre outras, medidas de força muscular de preensão nas duas mãos, questões relacionadas à dificuldade na realização das atividades diárias, estudo densitométrico da coluna lombar e quadril e bioquímica para determinação dos níveis de calcidiol.
Resultados: Valores de calcidiol ≥20 ng / mL foram associados ao aumento da força muscular de preensão em ambas as mãos. Após o ajuste para idade, sexo, IMC e sazonalidade, os níveis de calcidiol <20 ng / mL foram associados de forma independente à diminuição da força de preensão muscular apenas na mão esquerda (OR = 2,35, IC 95% 1,03-5, 38) Da mesma forma, a incapacidade ou dificuldade em "pegar um livro ou objeto em uma prateleira alta" e "sair da cama" foi significativamente associada a níveis de calcidiol <20 ng / mL. Níveis de calcidiol <20 ng / mL foram associados a maiores perdas de DMO no colo do fêmur e no quadril total. Essas associações foram mantidas na análise multivariada.
Conclusões: A manutenção de níveis de calcidiol ≥20 ng / mL foi associada a maior força de preensão muscular nas mãos, manutenção das atividades diárias e menor perda de DMO no quadril. Este estudo corrobora a utilidade de manter níveis adequados de vitamina D para manter a função músculo-esquelética.
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Este artigo é uma cópia com adaptação para o português do Artigo Original "Gómez Alonso, C., et al. "Niveles de calcidiol y mantenimiento de la función muscular, capacidad funcional y densidad mineral ósea en población española no seleccionada." Revista de Osteoporosis y Metabolismo Mineral 11.1 (2019): 6-11." Esta Cópia com adaptação para o Português segue os preceitos Creative Commons CC BY 4.0 ( https://creativecommons.org/licenses/by/4.0/deed.pt_BR ) disponibilizado pelo periódico responsável pela publicação original ( http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1889-836X2019000100002&lng=es&nrm=iso&tlng=es ).
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