Abstract
Introduction: Vitamin D has beneficial effects that supposedly contribute to the maintenance of musculoskeletal function.
Objective: To analyze in an unselected population the effect of calcidiol levels on the muscular function of both hands, on the activities of daily living and on changes in bone mineral density (BMD).
Material and methods: The cohort of the EVOS study was used, which performed, among others, measurements of muscle strength of grasping both hands, questions related to the difficulty in performing daily activities, densitometric study of the lumbar and hip spine and biochemistry for determination calcidiol levels.
Results: Calcidiol values ≥20 ng / mL were associated with increased grip muscle strength in both hands. After adjusting for age, sex, BMI and seasonality, calcidiol levels <20 ng / mL were independently associated with decreased muscle grip strength only in the left hand (OR = 2.35, 95% CI 1.03 -5, 38) Likewise, the inability or difficulty in "picking up a book or object on a high shelf" and "getting out of bed" was significantly associated with calcidiol levels <20 ng / mL. Calcidiol levels <20 ng / mL were associated with greater losses of BMD in the femoral neck and in the total hip. These associations were maintained in the multivariate analysis.
Conclusions: The maintenance of calcidiol levels ≥20 ng / mL was associated with greater muscle grip strength in the hands, maintenance of daily activities and less loss of BMD in the hip. This study corroborates the usefulness of maintaining adequate levels of vitamin D to maintain musculoskeletal function.
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Este artigo é uma cópia com adaptação para o português do Artigo Original "Gómez Alonso, C., et al. "Niveles de calcidiol y mantenimiento de la función muscular, capacidad funcional y densidad mineral ósea en población española no seleccionada." Revista de Osteoporosis y Metabolismo Mineral 11.1 (2019): 6-11." Esta Cópia com adaptação para o Português segue os preceitos Creative Commons CC BY 4.0 ( https://creativecommons.org/licenses/by/4.0/deed.pt_BR ) disponibilizado pelo periódico responsável pela publicação original ( http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1889-836X2019000100002&lng=es&nrm=iso&tlng=es ).
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