PERDA AUDITIVA INDUZIDA POR RUÍDO: PREVENÇÃO, DIAGNÓSTICO PRECOCE E TRATAMENTOS EMERGENTES

Authors

  • Daniella Rodrigues de Carvalho INAPÓS
  • Geovana Nabak dos Reis INAPÓS
  • João Pedro Vigano Contini INAPÓS
  • Theo Carneiro de Almeida Faria INAPÓS
  • Maria Paula Maiolini INAPÓS
  • Isabelle Sant'Ana Claretiano
  • Matheus Felicidade USCS
  • Emanuelle Carmo Rocha Ulbra
  • Isabela Barros Pedroso Ulbra
  • Glauber Farias da Silva Junior UASS
  • Maria Thereza Santos Bandeira Salgado FAMENE
  • Diogo de Lima Ramos FASM
  • Milena Souza de Oliveira FASM

DOI:

https://doi.org/10.36557/2674-8169.2025v7n2p979-989

Keywords:

Perda auditiva, prevenção, Manejo

Abstract

This article reviews the scientific literature on noise-induced hearing loss (NIHL), focusing on prevention, early diagnosis, and emerging treatments. The research was conducted in the PubMed, Scopus, and Web of Science databases, using the terms "Noise-induced hearing loss, Prevention, Early diagnosis, Emerging treatments." The analysis reveals that noise-induced hearing loss is a progressive and irreversible condition caused by prolonged exposure to high sound levels, mainly in work, leisure, or music environments. Prevention is considered the most effective strategy, emphasizing the use of proper hearing protection and public awareness of noise risks. Furthermore, early diagnosis is crucial to halt the progression of the condition, with regular audiometric exams, especially in populations exposed to high noise levels. Advances in the treatment of NIHL include the development of pharmacological and genetic therapies, as well as the use of more sophisticated hearing devices, such as cochlear implants and hearing amplification systems. Recent studies also explore the potential of regenerative therapies, such as hair cell stimulation and stem cell therapy, showing promising results. These emerging approaches may, in the future, transform the treatment and recovery of hearing function in patients with NIHL.

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References

CUNNINGHAM, L. L.; TUCCI, D. L. Noise-induced hearing loss: A modern epidemic. Otolaryngologic Clinics of North America, v. 50, n. 3, p. 439-450, 2017. https://doi.org/10.1016/j.otc.2017.02.003.

JI, M.; LIU, S.; LI, J. Pharmacological interventions for noise-induced hearing loss: The current status of clinical trials. International Journal of Molecular Sciences, v. 22, n. 14, p. 7411, 2021. https://doi.org/10.3390/ijms22147411.

KIKUCHI, M.; YAMASHITA, D.; MATSUMOTO, M.; et al. Stem cell therapy for noise-induced hearing loss: Advances and challenges. Stem Cells Translational Medicine, v. 10, n. 8, p. 1052-1060, 2021. https://doi.org/10.1002/sctm.20-0475.

KRAUS, N.; KAPLAN, H. L.; LEE, K. M. Auditory plasticity and noise-induced hearing loss: Implications for therapy. Journal of the Association for Research in Otolaryngology, v. 22, n. 2, p. 289-300, 2021. https://doi.org/10.1007/s10162-021-00871-3.

KUJAWA, S. G.; LIBERMAN, M. C. Acceleration of age-related hearing loss by early noise exposure: Evidence of a misspent youth. Journal of Neuroscience, v. 29, n. 11, p. 4079-4085, 2009. https://doi.org/10.1523/JNEUROSCI.0058-09.2009.

LIU, Z.; ZHANG, C.; WANG, Q.; et al. Cochlear hair cell regeneration: The potential for stem cell therapy. Frontiers in Neuroscience, v. 14, p. 578, 2020. https://doi.org/10.3389/fnins.2020.00578.

NELSON, D. I.; REYNA, V.; RIVERA, M. The global burden of occupational noise-induced hearing loss. American Journal of Industrial Medicine, v. 48, n. 6, p. 507-511, 2005. https://doi.org/10.1002/ajim.20223.

O'DONOGHUE, G. M.; HERRMANN, K. L.; CRESSWELL, P. Cochlear implants: Advances and innovations. Journal of the American Medical Association, v. 323, n. 9, p. 838-848, 2020. https://doi.org/10.1001/jama.2020.1258.

SANCHEZ, J. L.; LOPEZ, P. J.; GARCÍA, E.; et al. Occupational noise exposure and hearing loss prevention programs. Journal of Occupational Health, v. 62, n. 1, p. e12136, 2020. https://doi.org/10.1002/1348-9585.12136.

WANG, J.; LIU, H.; ZHANG, Y. Advances in noise-induced hearing loss: From pathophysiology to therapeutics. Journal of Otology, v. 15, n. 3, p. 127-134, 2020. https://doi.org/10.1016/j.joto.2020.06.002.

YAMAMOTO, H.; KOBAYASHI, Y.; HARA, A. Noise-induced hearing loss: Mechanisms, prevention, and clinical management. International Journal of Environmental Research and Public Health, v. 16, n. 17, p. 3157, 2019. https://doi.org/10.3390/ijerph16173157.

Published

2025-02-21

How to Cite

Rodrigues de Carvalho, D., Reis, G. N. dos, Contini, J. P. V., Faria, T. C. de A., Maiolini, M. P., Sant’Ana, I., Felicidade, M., Rocha, E. C., Pedroso, I. B., Junior, G. F. da S., Salgado, M. T. S. B., Ramos, D. de L., & Oliveira, M. S. de. (2025). PERDA AUDITIVA INDUZIDA POR RUÍDO: PREVENÇÃO, DIAGNÓSTICO PRECOCE E TRATAMENTOS EMERGENTES . Brazilian Journal of Implantology and Health Sciences, 7(2), 979–989. https://doi.org/10.36557/2674-8169.2025v7n2p979-989