Impacto do uso de corticosteroides intranasais no manejo de rinossinusite crônica
DOI:
https://doi.org/10.36557/2674-8169.2024v6n8p3674-3682Palavras-chave:
Corticosteroides; Rinossinusite; Tratamento.Resumo
Este artigo revisa a literatura médica sobre a eficácia dos corticosteroides intranasais e tópicos no tratamento da rinossinusite crônica. A busca foi conduzida no PubMed usando os descritores “Nasal Corticosteroids”, “Topical Corticosteroids”, “Chronic Rhinosinusitis”, e “Treatment”. A análise revelou que a administração pré-operatória de corticosteroides sistêmicos é eficaz na redução da inflamação eosinofílica e na melhoria do planejamento cirúrgico, enquanto os corticosteroides tópicos demonstraram benefícios na função olfativa e na redução dos sintomas e tamanho dos pólipos. Além disso, abordagens combinadas e novas alternativas, como o mepolizumabe, mostraram oferecer benefícios adicionais e melhorar a adesão ao tratamento, destacando a necessidade de estratégias integradas para o manejo da rinossinusite crônica refratária.
Downloads
Referências
AKIYAMA, K. et al. Impact of preoperative systemic corticosteroids on the histology and diagnosis of eosinophilic chronic rhinosinusitis. *International Archives of Allergy and Immunology*, v. 179, n. 1, p. 1-8, 2019. PMID: 30799396. Clinical Trial.
BANGLAWALA, S. M. et al. Olfactory outcomes in chronic rhinosinusitis with nasal polyposis after medical treatments: a systematic review and meta-analysis. *International Forum of Allergy & Rhinology*, 2023.
BOGNANNI, A. et al. Topical corticosteroids for chronic rhinosinusitis with nasal polyposis: GRADE systematic review and network meta-analysis. *Journal of Allergy and Clinical Immunology*, v. 149, n. 5, p. 1615-1627, 2022. PMID: 35970310.
BORISH, L. et al. Evaluating enrollment and outcome criteria in trials of biologics for chronic rhinosinusitis with nasal polyps. *Annals of Allergy, Asthma & Immunology*, v. 129, n. 4, p. 408-413, 2022. PMID: 35398492. Review.
CANTONE, E. et al. Effect of sodium hyaluronate added to topical corticosteroids in chronic rhinosinusitis with nasal polyposis. *American Journal of Rhinology & Allergy*, v. 30, n. 3, p. 165-170, 2016. PMID: 27302143.
CHUPP, G. et al. Mepolizumab reduces systemic corticosteroid use in chronic rhinosinusitis with nasal polyps. *Journal of Allergy and Clinical Immunology: Practice*, v. 11, n. 1, p. 111-120, 2023. PMID: 37586475. Clinical Trial.
FENG, S. et al. Effects of mobile phone WeChat services improve adherence to corticosteroid nasal spray treatment for chronic rhinosinusitis after functional endoscopic sinus surgery: a 3-month follow-up study. *European Archives of Oto-Rhino-Laryngology*, v. 274, n. 7, p. 2567-2573, 2017. PMID: 27822702. Clinical Trial.
FU, Z. et al. The impact of postoperative topical corticosteroid irrigation on short-term efficacy and olfactory function in patients with chronic rhinosinusitis with nasal polyps following endoscopic sinus surgery. *Minerva Medica*, v. 114, n. 2, p. 123-130, 2023. PMID: 37947783.
HEAD, K. et al. Short-course oral steroids alone for chronic rhinosinusitis. *Cochrane Database of Systematic Reviews*, v. 2016, n. 2, p. CD008659, 2016. PMID: 27113367. Review.
IKEDA, K. et al. Postoperative management of eosinophilic chronic rhinosinusitis with nasal polyps: impact of high-dose corticosteroid nasal spray. *International Archives of Otorhinolaryngology*, v. 23, n. 2, p. 184-190, 2019. PMID: 30647792.
LEUNG, R. M. et al. Should oral corticosteroids be used in medical therapy for chronic rhinosinusitis? A risk analysis. *Laryngoscope*, v. 131, n. 6, p. 1282-1287, 2021. PMID: 32633822.
LIU, C. M. et al. Impact of saline irrigation and topical corticosteroids on the postsurgical sinonasal microbiota. *International Forum of Allergy & Rhinology*, v. 5, n. 6, p. 548-554, 2015. PMID: 25556553.
PARIKH, A. et al. Topical corticosteroids in chronic rhinosinusitis: a randomized, double-blind, placebo-controlled trial using fluticasone propionate aqueous nasal spray. *Rhinology*, v. 39, n. 2, p. 92-96, 2001. PMID: 11486442. Clinical Trial.
SMITH, K. A. et al. Impact of continued medical therapy in patients with refractory chronic rhinosinusitis. *International Forum of Allergy & Rhinology*, v. 4, n. 5, p. 393-398, 2014. PMID: 24166890.
SNIDVONGS, K. et al. Topical steroid for chronic rhinosinusitis without polyps. *Cochrane Database of Systematic Reviews*, v. 2011, n. 6, p. CD009760, 2011. PMID: 21833974. Updated. Review.
Downloads
Publicado
Como Citar
Edição
Seção
Licença
Copyright (c) 2024 Luiz Henrique Santos, Miguel Isaias Lopes Silveira, Giulia Gabrielly de Lima, João Vitor Ferreira Assunção de Araújo, Maria Fernanda da Silva Rodrigues, Débora, Paloma, Vasques, Paula, Fabrícia, Rafaela, Raphael, Maria Laura, Mariana, José, Thayse Velez Belmont de Brito, Nilber Acioli de Almeida Junior, Clara Beatriz Cesário de Oliveira, Amanda Ramalho Rocha
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Os autores são detentores dos direitos autorais mediante uma licença CCBY 4.0.
