Artificial Intelligence in Clinical Medicine: Applications in Early Diagnosis, Prognosis, and Support for Medical Decision-Making
DOI:
https://doi.org/10.36557/2674-8169.2026v8n5p501-515Keywords:
Artificial intelligence; Machine learning; Deep learning; Digital medicineAbstract
Introduction: Artificial intelligence (AI) has established itself as one of the most promising technologies for transforming contemporary medicine. The development of machine learning and deep learning algorithms has enabled the analysis of large volumes of clinical data, contributing to improvements in the early diagnosis of diseases, risk stratification, and support for clinical decision-making. Objective: To critically analyze the scientific evidence regarding the application of artificial intelligence in medical practice, with an emphasis on assisted diagnostic systems, predictive prognostic models, and clinical decision support tools. Methodology: A systematic literature review was conducted in the PubMed, Scopus, and Web of Science databases, considering publications between 2018 and 2025. The search strategy used descriptors related to artificial intelligence and medical practice, combined with Boolean operators AND and OR. Results: The evidence demonstrates that artificial intelligence algorithms have a high capacity to identify complex clinical patterns and assist in the early diagnosis of various conditions, including sepsis, cardiovascular diseases, and cardiac arrhythmias. Furthermore, predictive models based on machine learning showed significant performance in predicting hospital mortality, clinical deterioration, and hospital readmissions. Conclusion: Artificial intelligence has high potential to improve medical practice, contributing to the development of more precise, personalized, and data-driven medicine. However, challenges related to the interpretability of algorithms, clinical validation, and data security still need to be overcome for a broad and safe implementation of these technologies.
Downloads
References
Topol EJ. High-performance medicine: the convergence of human and artificial intelligence. Nat Med. 2019;25:44-56.
Rajkomar A, Dean J, Kohane I. Machine learning in medicine. N Engl J Med. 2019;380:1347-1358.
Beam AL, Kohane IS. Big data and machine learning in health care. JAMA. 2018;319:1317-1318.
Esteva A, Kuprel B, Novoa RA, et al. Dermatologist-level classification of skin cancer with deep neural networks. Nature. 2017;542:115-118.
Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315:801-810.
Nemati S, Holder A, Razmi F, et al. An interpretable machine learning model for accurate prediction of sepsis in the ICU. Crit Care Med. 2018;46:547-553.
Kwon JM, Kim KH, Jeon KH, et al. Development and validation of deep-learning-based models for prediction of 1-year mortality in patients with heart failure. J Am Heart Assoc. 2019;8:e012210.
Attia ZI, Kapa S, Lopez-Jimenez F, et al. Screening for cardiac contractile dysfunction using an artificial intelligence–enabled electrocardiogram. Nat Med. 2019;25:70-74.
Rajkomar A, Dean J, Kohane I. Scalable and accurate deep learning with electronic health records. NPJ Digit Med. 2019;2:18.
Ben-Israel D, Oren O, Goldberg-Stein S, et al. Machine learning for prediction of cardiovascular events in heart failure patients. J Card Fail. 2020;26:400-409.
Kang S, Lee S, Kim J, et al. Deep learning for ECG analysis: detection of complex arrhythmias. Comput Biol Med. 2021;133:104377.
Chen R, Stewart WF, Sun J, et al. Using deep learning to predict hospital readmissions from electronic health records. PLoS One. 2020;15:e0235793.
Kueper J, Sulieman L, Singh K, et al. Large-scale machine learning for clinical decision support: opportunities and challenges. J Am Med Inform Assoc. 2022;29:1511-1521.
Singhal K, Kumar S, Raghavan V, et al. Large language models encode clinical knowledge. Nature. 2023;614:488-496.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Amábile Luiza Cordenonsi, Camila Brugnago, Henrique Deboni, Naiara Caroline Ludwig, Camila Bellato, Felipe Chiodi, Aretuza Da Silva, Murieli Carbonare, André luis Hermam, Gabriela Sabedot, Thaís Cristina Moreira Mattos Neiva, Isabela Borella Da Silva

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors are copyright holders under a CCBY 4.0 license.



