O cuidado farmacêutico em farmácias magistrais: uma revisão integrativa da literatura brasileira

Abstract

Compounding pharmacies play a key role in personalized pharmacotherapy, as they are responsible for the preparation of customized formulations tailored to individual patient needs. However, despite this strategic potential, pharmaceutical care is not yet fully integrated into the daily routine of these establishments. Factors such as a predominant productivity-oriented model, lack of solid clinical training, and absence of care protocols hinder the consolidation of a patient-centered practice. This review aimed to analyze the current state of pharmaceutical care practices in Brazilian compounding pharmacies, identify the main barriers to its effective implementation, and discuss alternatives to promote its integration within healthcare services. An integrative literature review was conducted based on searches performed between January and February 2024 in the databases BVS, Google Scholar, SciELO, and CAPES Journals Portal. The descriptors used were: “magistral pharmacy,” “compounding pharmacy,” “pharmaceutical care,” and “pharmaceutical attention,” combined using the Boolean operator AND. Inclusion criteria were full-text articles published between 2013 and 2023 in Portuguese, English, or Spanish that directly or indirectly addressed the proposed topic. A total of 795 studies were retrieved, with 8 meeting the inclusion criteria for final analysis. The findings were grouped into three thematic axes: barriers to care implementation, professional practices and perceptions, and strategies for institutionalizing pharmaceutical care. Although favorable regulatory frameworks exist, such as CFF Resolution No. 746/2023, the effective integration of pharmaceutical care into compounding pharmacies remains limited. Nevertheless, successful experiences demonstrate that qualified counseling, pharmacotherapeutic follow-up, and health education can improve therapeutic outcomes and strengthen pharmacist-patient relationships. There is an urgent need to reposition the compounding pharmacist as an active healthcare provider, enhancing clinical practice and promoting comprehensive, patient-centered care.