Sialolitíase e alterações patológicas das glândulas salivares: uma abordagem estomatológica – Revisão integrativa da literatura

Authors

DOI:

https://doi.org/10.36557/2674-8169.2025v7n5p1242-1256

Keywords:

Sialolitíase; Glândulas Salivares; Estomatologia; Diagnóstico Oral; Doenças das Glândulas Salivares.

Abstract

Introduction: Salivary glands perform essential functions in the stomatognathic system, such as oral lubrication, initiation of digestion and protection against microorganisms. Sialolithiasis, characterized by the formation of sialoliths in the ducts or glandular parenchyma predominantly in the submandibular gland, stands out for its high prevalence and clinical impact, generating pain, edema and recurrent infections.Objectives:
To compile and critically analyze the scientific evidence on sialolithiasis, focusing on its etiology, pathophysiology, clinical manifestations, and diagnosis from a stomatological perspective.Methodology: An integrative literature review was conducted through searches in PubMed, Scopus, SciELO, BVS, LILACS, and SpringerLink databases, including studies published between 2010 and 2025. The descriptors “Sialolithiasis”, “Salivary Glands”, “Salivary Gland Diseases”, “Oral Diagnosis” and “Stomatology” were used, combined with Boolean operators. After screening and critical reading, 13 studies met the inclusion criteria. Conclusion: Sialolithiasis has a multifactorial etiology, including anatomical, biochemical, and infectious factors. Diagnosis is primarily clinical and radiographic, with sialendoscopy highlighted as a minimally invasive technique. Treatment ranges from conservative approaches to surgical procedures, and prevention relies on proper hydration and oral hygiene. The stomatologist plays a crucial role in early diagnosis and effective management of the condition.

Downloads

Download data is not yet available.

References

DIAS, J. P. L. et al. Giant sialolith of parotid duct: a rare entity. Autopsy and Case Reports, São Paulo, v. 11, e2021300, 2021. https://doi.org/10.4322/acr.2021.300.

FRUET, F. N. et al. Gigantic cervical abscess caused by submandibular sialolithiasis: case report. Brazilian Journal of Otorhinolaryngology, São Paulo, v. 82, n. 3, p. 346–349, 2016. https://doi.org/10.1016/j.bjorl.2015.05.021.

HARRILL, J. A. et al. Sialolithiasis: current imaging and management trends. Otolaryngologic Clinics of North America, Philadelphia, v. 56, n. 1, p. 55–68, 2023. https://doi.org/10.1016/j.otc.2022.08.004.

KRAAIJ, S. et al. Bacterial biofilms and calcifications in salivary stones: a role in sialolithogenesis? Journal of oral and Maxillofacial Surgery, Amsterdam, v. 77, n. 4, p. 699.e1–699.e8, 2019. https://doi.org/10.1016/j.joms.2018.11.013.

KROLL, T. et al. Protein composition of submandibular salivary gland stones: insights into their formation. Biological Trace Element Research, [S. l.], v. 200, p. 4747–4754, 2022. DOI: 10.1007/s12011-022-03455-2. Disponível em: https://link.springer.com/article/10.1007/s10534-022-00465-7. Acesso em: 6 maio 2025.

LILIA, C. C. et al. Cutaneous fistula secondary to submandibular sialolithiasis: a case report and literature review. International Journal of Surgery Case Reports, Amsterdam, v. 82, p. 105912, 2021. https://doi.org/10.1016/j.ijscr.2021.105912.

ŁYSIAK, M. et al. Structural analysis and formation process of submandibular gland sialoliths: A study of 30 cases. Diagnostics, [S. l.], v. 13, n. 13, p. 2287, 2023. DOI: 10.3390/diagnostics13132287. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382579/. Acesso em: 6 maio 2025.

MURRAY, P. et al. Sialolithiasis: structural and chemical analysis of 23 salivary stones. European Archives of Oto-Rhino-Laryngology, [S. l.], v. 276, p. 1801–1810, 2019. DOI: 10.1007/s00405-019-05445-1. Disponível em: https://link.springer.com/article/10.1007/s00405-019-05445-1. Acesso em: 6 maio 2025.

ODDS, F. C. et al. Salivary gland infections and sialolithiasis. In: BEESON, P. B. et al. Harrison’s Principles of Internal Medicine. 20. ed. New York: McGraw-Hill, 2019. Cap. 50, p. 421–426.

RODRIGUES, M. A. et al. Sialolithiasis of minor salivary glands: a case series and literature review. Journal of Clinical and Experimental Dentistry, Barcelona, v. 13, n. 4, p. e412–e417, 2021. https://doi.org/10.4317/jced.57839.

RZYMSKA-GRALA, I. et al. The usefulness of ultrasound and conventional radiography in the initial diagnosis of salivary gland calculi. Dentomaxillofacial Radiology, London, v. 39, n. 6, p. 361–365, 2010. https://doi.org/10.1259/dmfr/53518874.

SANTOS, P. R. et al. Sialolithiasis: pathogenesis, diagnosis and management strategies. Revista Brasileira de Otorrinolaringologia, São Paulo, v. 85, n. 4, p. 472–479, 2019. https://doi.org/10.1016/j.bjorl.2018.08.001.

SHARMA, A. et al. Role of sialoendoscopy in management of sialolithiasis: our experience. Journal of Oral Biology and Craniofacial Research, Amsterdam, v. 9, n. 2, p. 151–155, 2019. https://doi.org/10.1016/j.jobcr.2018.10.002.

Published

2025-05-22

How to Cite

Alencar, D. T. A. C. V., de Carvalho, Y. S., Meneses, A. L. D. da S., de Almeida, L. M. F., Dias, A. B. A., Freitas, M. L. R. F., de Alencar, P. H. M., & Moreira, T. H. G. (2025). Sialolitíase e alterações patológicas das glândulas salivares: uma abordagem estomatológica – Revisão integrativa da literatura. Brazilian Journal of Implantology and Health Sciences, 7(5), 1242–1256. https://doi.org/10.36557/2674-8169.2025v7n5p1242-1256