Keywords
Vasculitis
Oral Ulcer
Erythema Nodosum
Autoimmunity
How to Cite
Abstract
This article aims to explore the pathophysiology, clinical manifestations, and therapeutic options of Behçet's Disease (BD) based on recent scientific publications. Studies published between 2019 and 2024, in English and Portuguese, were selected from the PubMed database, using terms related to the disease. BD is a chronic inflammatory vasculitis of autoimmune origin, which can affect vessels of different calibers and compromise multiple systems of the body. Its main manifestations include recurrent oral and genital ulcers, skin lesions, joint involvement, and gastrointestinal and neurological symptoms. Among the most serious complications, uveitis stands out, which can progress to irreversible visual loss. The diagnosis is essentially clinical and follows the criteria of the International Study Group for Behçet's Disease, based on the recurrence of manifestations. Although there is no cure, treatment aims to control inflammation and reduce the risk of complications, with immunosuppressants and anti-inflammatories being the main therapeutic approaches. Early diagnosis and ongoing medical monitoring are essential to improve the prognosis and quality of life of patients.
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Copyright (c) 2025 Thiago José Islanderson dos Santos Castro, Josiane Simplicio de Abreu , João Pedro Gomes Pequeno Gonzaga, Rômulo José Falcão Farias, Brenda Lorenna de Jesus Araújo, Beatriz Bastos Santos , Maria Gabriela Lermen de Souza , Liz Silva Mariano , Pedro Lucas Pessoa Cardoso , Gabriel Alves Da Silva Santiago , Ana Caroline dos Santos Sousa , Camila Camaia Souza Winter , Caio Gabriel Ferreira Souza , Gabriela Castro de França , Brenna Martins Barboza , Emanoele Batista Rafael, Henrique Lima Martins, Monique Lima Martins
