Use of Vitamin C in the Mucosal Healing Process after Tooth Extractions
DOI:
https://doi.org/10.36557/2674-8169.2025v7n3p2052-2061Keywords:
Ascorbic Acid, Wound Healing, Surgery, OralAbstract
Objective: This study aims to evaluate the role of Vitamin C in the healing process of the oral mucosa after tooth extractions, analyzing its biochemical mechanisms, clinical benefits, and potential interdisciplinary applications in healthcare. Materials and Methods: A systematic review of scientific literature was conducted using databases such as PubMed, Scielo, and BVS Bireme. Studies investigating the effects of Vitamin C on wound healing, collagen synthesis, angiogenesis, oxidative stress reduction, and its influence on periodontal health and post-extraction recovery were analyzed. In vitro and in vivo studies were included to provide a comprehensive overview of its biological and clinical implications. Results: The findings indicate that Vitamin C plays a crucial role in the post-extraction healing process by promoting collagen synthesis, enhancing angiogenesis, and reducing oxidative stress, leading to faster tissue repair. Its immunomodulatory properties also contribute to a lower incidence of infections and complications such as alveolitis. Additionally, its antioxidant action helps prevent cellular damage, while its remineralizing effect aids in maintaining periodontal and dental health. Studies also highlight its potential benefits in implant osseointegration and periodontal disease prevention, reinforcing its relevance in clinical dental practice. Conclusion: Vitamin C is a key element in optimizing oral tissue regeneration, offering multiple benefits that go beyond post-extraction healing. Its interdisciplinary approach, integrating dentistry with nutrition and medicine, enhances clinical outcomes and patient care. Considering its wide-ranging effects, further research and clinical protocols should be encouraged to maximize its application in dentistry.
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Copyright (c) 2025 Marvin Gonçalves Duarte, Gracielle Radja Rodrigues de Lima, Brunno Stephany Lima de Paula, Diogo Acioli Filizola Germano, Rosana Maria Coelho Travassos, Eudoro de Queiroz Marques Filho, Rodolfo Scavuzzi Carneiro Cunha, Ailton Coelho de Ataíde Filho, Manoel Arthur Dias de Oliveira Antonino, Luciano Barreto Silva

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