Regenerative Orthopedics: The Role of Biological Therapies in Joint Reconstruction
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Keywords

Biological therapies; Joint regeneration; Platelet-rich plasma; Mesenchymal stem cells; Hyaluronic acid.

How to Cite

Paes Espindola de Souza, G., Costa Shockness , D., Gregório Nolasco , H., Lucena Cangussu, G., Morgado e Souza, H., Abreu Tsutsumi , A., & Almeida , A. L. B. da S. (2025). Regenerative Orthopedics: The Role of Biological Therapies in Joint Reconstruction. Brazilian Journal of Implantology and Health Sciences, 7(1), 745–754. https://doi.org/10.36557/2674-8169.2025v7n1p745-754

Abstract

This study explores the impact of biological therapies on joint regeneration, focusing on their clinical applications, efficacy and limitations. The research adopts a narrative bibliographic review, analyzing articles published between 2014 and 2024 in renowned scientific databases. Biological therapies, such as platelet-rich plasma, mesenchymal stem cells, and hyaluronic acid, have demonstrated potential in restoring joint tissues and relieving symptoms in conditions such as osteoarthritis and joint injuries. The findings indicate significant advances, but also highlight challenges, such as the standardization of protocols and the variability of results between studies. It is concluded that, although promising, biological therapies still require additional studies to consolidate their effectiveness and expand clinical use.

https://doi.org/10.36557/2674-8169.2025v7n1p745-754
PDF (Português (Brasil))

References

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Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2025 Guilherme Paes Espindola de Souza, Danilo Costa Shockness , Henrique Gregório Nolasco , Gabriel Lucena Cangussu, Henrique Morgado e Souza, Ariane Abreu Tsutsumi

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