Ludwig's angina of odontogenic origin: case report in a hospital emergency unit in Pernambuco.
DOI:
https://doi.org/10.36557/2674-8169.2025v7n1p426-440Keywords:
Ludwig's Angina, Vías Aéreas, Diagnosis TreatmentAbstract
Introduction: Odontogenic infections, derived from dental problems, can spread to the underlying facial spaces, becoming complex. A potentially fatal diffuse cellulitis of the soft tissues, usually located in the second and third lower molars. Predisposing factors include recent tooth extraction and exposed fractures of the mandible, which are also related. The most affected patients are men, aged between six and seventy-eight years. Among the main complications is Ludwig's Angina. Objective: This article describes a clinical case report in which the two diseases are associated. Case report: A 73-year-old female patient with a history of hypertension and heart disease, without a previous diagnosis of diabetes, was admitted to the Oral and Maxillofacial Surgery and Traumatology service of a reference hospital in Pernambuco, presenting a serious clinical condition that had evolved over four days. Symptoms included intense pain, cervical edema, fever and progressive respiratory difficulty. The patient had an increase in volume in the submandibular and submental regions for four days. The intraoral clinical examination revealed the right lower alveolar bone as the focus of infection and intra- and extraoral floating point. Preoperative examinations and hospitalization were requested. The patient underwent surgery under general anesthesia and orotracheal intubation, under videolaparoscopy, for drainage of an abscess of odontogenic origin, bilateral mandibular osteoplasty and insertion of a Penrose drain. The patient received intensive treatment with surgical drainage, antibiotic therapy and respiratory support. During hospitalization, the patient presented episodes of clinical worsening, controlled with additional surgical interventions and pharmacological adjustments. Discussion: Ludwig's angina is a relatively uncommon gangrenous cellulitis and edema of the soft tissues of the neck and floor of the mouth. It begins with the invasion of the submandibular, sublingual and submental spaces by anaerobic bacteria, which can spread through the mediastinum. It requires early diagnosis and immediate treatment due to its rapid progression and high risk of respiratory complications. In elderly patients, the presence of comorbidities, such as hypertension, can make management difficult, increasing the complexity of treatment. Conclusion: Early diagnosis and surgical treatment require an assertive approach, especially in cases that evolve rapidly. Therefore, early symptoms are often nonspecific, and delayed treatment can lead to fatal complications.
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References
CAMARGOS, Felipe da Mata et al. Infecções odontogênicas complexas e seu perfil epidemiológico. Revista de Cirurgia e Traumatologia Buco-maxilo-facial, v. 16, n. 2, p. 25-30, 2016.
LOU, Y.; SUN, Z.; MA, H.; CAO, D.; SUN, M.; WANG, Q.; WANG, J.; ZHUO, Q.; TAO, R.; YING, B.; LIU, Y.; YU, M.; WANG, H. Odontogenic infections in the antibiotic era: approach to diagnosis, management, and prevention. Infection, 2023. Disponível em: https://doi.org/10.1007/s15010-023-02117-5.
MARTINS, Luciano et al. Angina de Ludwig – considerações sobre conduta e relato de caso. Revista do Instituto de Ciências da Saúde, v. 27, n. 4, p. 413-416, 2009.
TAILOR, B. V. et al. Parapharyngeal and floor-of-mouth abscess secondary to tonsillar phlegmon: A rare and unusual cause of Ludwig's angina. Clin Case Rep, v. 10, n. 9, p. e6325, 2022. Disponível em: https://doi.org/10.1002/ccr3.6325.
OSAGHAE, I. P. et al. Ludwig’s angina in Nigeria: The disease of the poor and health inequality! The Surgeon, 2021. Disponível em: https://doi.org/10.1016/j.surge.2021.05.007.
PARKER, E.; MORTIMORE, G. Ludwig’s angina: a multidisciplinary concern. British Journal of Nursing, v. 28, n. 9, p. 547–551, 2019. Disponível em: https://doi.org/10.12968/bjon.2019.28.9.547.
BOSCOLO-RIZZO, P.; DA MOSTO, M. C. Submandibular space infection: a potentially lethal infection. International Journal of Infectious Diseases, v. 13, n. 3, p. 327–333, 2009. Disponível em: https://doi.org/10.1016/j.ijid.2008.07.007.
QUINN, F. B. Jr. Ludwig angina. Arch Otolaryngol Head Neck Surg, v. 125, n. 5, p. 599, maio 1999. Disponível em: https://doi.org/10.1001/archotol.125.5.599.
VALLÉE, M. et al. Ludwig’s angina: A diagnostic and surgical priority. International Journal of Infectious Diseases, v. 93, p. 160–162, 2020. Disponível em: https://doi.org/10.1016/j.ijid.2020.01.028.
XÁ, A.; AHMED, I.; HASSAN, S.; SAMOON, A.; ALI, B. Avaliação da ultrassonografia como ferramenta diagnóstica no manejo de infecções do espaço facial de cabeça e pescoço: um estudo clínico. Jornal Nacional de Cirurgia Maxilofacial, v. 6, n. 1, p. 55-61, jan.-jun. 2015. Disponível em: https://doi.org/10.4103/0975-5950.168213.
SHIH, C. C.; WANG, J. C.; CHEN, S. J.; HSU, Y. P. Focused ultrasound assists in diagnosis and management of difficult airway in Ludwig's angina. Journal of Medical Ultrasound, v. 27, n. 2, p. 101-103, abr.-jun. 2019. Disponível em: https://doi.org/10.4103/JMU.JMU_95_18.
LIN, Qing-Ling et al. Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients. Journal of Dental Sciences, v. 15, n. 4, p. 445-450, 2020. Disponível em: https://doi.org/10.1016/j.jds.2019.10.004.
PETRIE VAN DER MERWE, Roxanne et al. The empirical use of aminoglycosides in Ludwig's angina based on bacterial analysis of 63 cases. Journal of Stomatology, Oral and Maxillofacial Surgery, v. 124, p. 101409, 2023. Disponível em: https://doi.org/10.1016/j.jormas.2023.101409.
MOVVA, H.; TAKSANDE, K. Desafios anestésicos em um paciente com angina de Ludwig: relato de caso. Cureus, v. 14, n. 10, e30570, 21 out. 2022. Disponível em: https://doi.org/10.7759/cureus.30570.
FERNANDES, S. L. et al. Complicações relativas às infecções odontogênicas: angina de Ludwig. Journal of Multidisciplinary Dentistry, v. 10, n. 1, p. 46-51, 2020.
SILVA, P. C. A. et al. Rara associação de angina de Ludwig e leishmaniose visceral: rápida intervenção e desfecho clínico favorável. The Brazilian Journal of Infectious Diseases, v. 26, p. 102476, 2022.
PARMAR, B. D. et al. Management of Ludwig's angina at a tertiary care hospital in western region of India. Cureus, v. 14, n. 3, e23311, 19 mar. 2022. Disponível em: https://doi.org/10.7759/cureus.23311.
TU, A.; GILBERT, J. D.; BYARD, R. W. Ludwig angina e morte súbita. Forensic Science, Medicine and Pathology, v. 17, p. 506–509, 2021. Disponível em: https://doi.org/10.1007/s12024-020-00350-0.
DE VASCONCELOS, Kamyla Souza; DA SILVA JUNIOR, Messias Froes; CAIRES, Nely Cristina Medeiros. Angina de Ludwig e suas complicações: estudo de caso de paciente internado em UTI de um hospital público na região norte do Brasil. Revista Eletrônica Acervo Saúde, v. 13, n. 7, p. e8033-e8033, 2021.
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Copyright (c) 2025 Eduardo Dias, Maria Eduarda, Juan Pablo , Clarice Calado, Wallison Melo, Arthur Ferreira, Letícia Teles, Laura Gomes, Thammirys Pinheiro, Andressa Sampaio, Pedro Brayner, Rennan Abreu

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