Keywords
Convulsões
Infecções virais
How to Cite
Abstract
Introduction: Febrile seizures are seizures that occur in children between 6 months and 5 years of age, when there is a sudden increase in body temperature, due to the immaturity of the central nervous system. Objectives: This study consists of a literature review that was carried out to identify and synthesize the available evidence on the mechanisms behind febrile seizures in children and their associations with infections. Methodology: Research carried out in December 2024, based on an integrative review of the scientific literature in the SciELo, BVS and PubMed databases. Results and Discussion: The pathophysiology of CF involves genetic factors and the immaturity of the central nervous system (CNS), which makes children more susceptible to febrile stimuli. The increase in temperature can impair electrical conduction in the CNS, triggering seizures. Conclusion: Understanding the pathophysiological mechanisms, including the immaturity of the central nervous system and the influence of genetic factors, is essential for the identification of risk factors and for adequate clinical management.
References
BEN, G. C. D. et al. Convulsão febril: Uma abordagem geral e seus principais aspectos. Anais do II Congresso Luso-Brasileiro de Atenção Integral à Saúde (On-line) – Resumos Expandidos, 2022.
CARVALHO, F. C. et al. Epilepsia, do diagnóstico ao tratamento: revisão de literatura / Epilepsy, from diagnosis to treatment: a literature review. Brazilian Journal of Development, v. 8, n. 2, p. 8988–8997, 3 fev. 2022.
CIVAN, A. B. et al. Evaluation of the risk factors for recurrence and the development of epilepsy in patients with febrile seizure. Arquivos de Neuro-Psiquiatria, v. 80, n. 08, p. 779–785, ago. 2022.
DIOGO, M. P. S. et al. Convulsão Febril em crianças: uma revisão abrangente de diagnóstico, manejo e prognóstico. Brazilian Journal of Implantology and Health Sciences, v. 6, n. 2, p. 1995–2003, 23 fev. 2024.
FARHAD HEYDARIAN; BAKHTIARI, E.; BAY, M. Risk factors of seizure and complex seizure in febrile children: a clinical study. BMC Pediatrics, v. 24, n. 1, 12 nov. 2024.
FONSECA, A. L. B.; BENAVIDES, V. M. S. Crise convulsiva febril em crianças: uma revisão narrativa. Revista Eletrônica Acervo Médico, v. 3, p. e9780–e9780, 21 fev. 2022.
GOMIDE-NOGUEIRA DE SÁ, A. C. M. et al. Febre Infantil e seu Manejo pelos Pais: Análise Quantitativa. Revista Brasileira de Ciências da Saúde, v. 22, n. 2, p. 117–124, 2018.
KLOC, M. L. et al. Recurrent febrile seizures alter intrahippocampal temporal coordination but do not cause spatial learning impairments. Epilepsia, v. 62, n. 12, p. 3117–3130, 25 set. 2021.
OZLEM TEKSAM et al. Practices of pediatric emergency physicians on the first febrile and afebrile seizures: a research in European Pediatric Emergency Medicine Survey Study. European Journal of Emergency Medicine, v. 29, n. 6, p. 455–457, 25 out. 2022.
PEREIRA, C. DOS S. et al. Uma revisão acerca da epilepsia: sua epidemiologia no mundo e seu tratamento / A review about epilepsy: its epidemiology in the world and its treatment. Brazilian Journal of Health Review, v. 5, n. 3, 7 jun, 2022.
RAFAEL ROCHA GONÇALVES et al. Avaliação Diagnóstica de Convulsões Febris: Desafios e Novas Perspectivas. Brazilian Journal of Implantology and Health Sciences, v. 6, n. 2, p. 2267–2278, 28 fev. 2024.
REZENDE MACHADO et al. Crise febril na Infância: Uma revisão dos principais conceitos Resumo Febrile seizure in childhood: A review of the main concepts. Residência Pediátrica, v. 8, n. 1, p. 11–16, 2018.
RYO SUGITATE et al. The effects of antihistamine on the duration of the febrile seizure: A single center study with a systematic review and meta-analysis. Brain and Development, v. 42, n. 2, p. 103–112, 1 fev. 2020.
TANAKA, T. et al. Clinical and laboratory characteristics of complex febrile seizures in the acute phase: a case-series study in Japan. BMC Neurology, v. 23, n. 1, 18 jan. 2023.
ZHANG, J.-Z. et al. [Clinical features of children with febrile seizures caused by Omicron variant infection]. PubMed, v. 25, n. 6, p. 595–599, 15 jun. 2023.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2024 Lauhanda Primo Borges, Frederico Souza Silva, Dayane Machado Borges , Giselle Leão Pereira, Carolina Aparecida Ribeiro, Dennis Russely de Vasconcelos Lima, Larissa Flávia Silva, Sam’la Helou Aly Abreu , Murillo de Almeida Cavalcanti Sabatini , Jorge Augusto Batista Borges, João Lucas Carvalho Valverde
