Abstract
Atopic dermatitis (AD) is a chronic, pruritic and inflammatory skin disease that occurs most often in children, but also affects adults. The clinical features of AD include skin dryness, scaling, erythema, secretion, crusting and lichenification. Itching is a characteristic of the disease and is responsible for much of the disease burden for patients, their families and caregivers. Treatment goals include reducing symptoms and signs, preventing exacerbations and minimization of therapeutic risks. Standard treatment modalities for the management of these patients are centered on the use of topical anti-inflammatory preparations and skin hydration, but Patients with severe disease may require phototherapy or systemic treatment. This review discusses the epidemiology, pathogenesis, clinical manifestations and diagnosis of AD, in addition to the approach to management of severe and refractory AD in children and adults.
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Copyright (c) 2024 Gabriela Vitória Giovanoni, Ana Paula Backes Dos Anjos, Jordão Luiz Moratelli Junior, Sarah Tairine Machado de Araújo, Nina Rafaella Figueiredo da Fonseca, Priscila Santos Rufino e Silva, Karen Ranieri Pacheco, Kauê Ranieri Pacheco, Laisa de Paula da Costa Lobato, Hálisson Ferreira Freitas Filho, Suany Lima de Souza, José Carlos Gomes Pereira, Victória Pacheco Kannenberg, Edson Bahri, Eduarda Mendes Lopes