PSORÍASE: MUITO ALÉM DA PELE- O IMPACTO SISTÊMICO E PSICOLÓGICO NO PACIENTE COM A DOENÇA IMUNOLÓGICA
DOI:
https://doi.org/10.36557/2674-8169.2024v6n9p1050-1061Keywords:
Psoriasis; Autoimmune; Emotional; Skin.Abstract
Psoriasis is a chronic, non-contagious, autoimmune inflammatory disease that affects approximately 2 to 5% of the world's population. Influenced by emotional, environmental and genetic factors, it manifests as reddish, scaly lesions, mainly in plaques on the skin. The disease involves epidermal hyperplasia and an inadequate immune response, with activated T lymphocytes and macrophages releasing cytokines such as TNF-α, which are fundamental in the inflammatory process. The pathophysiology includes changes in keratinocytes and the immune response, with involvement of cells such as keratinocytes and dendritic cells, resulting in conditions such as vulgaris, guttate, erythrodermic, inverse and palmoplantar psoriasis. Treatments include the use of emollients, vitamin D analogues, methotrexate and immunobiologicals, in addition to alternative therapies such as aloe vera, which has anti-inflammatory and healing properties, helping to reduce symptoms.
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Copyright (c) 2024 Raphael Siza de Oliveira e Oliveira, Thiago Silva Zanuto, Camila Melo de Freitas Oliveira, Helena Braule Pinto Simeão, Igor Henrique Correia Magalhaes, Isabela Abud de Andrade, Joana Bader Sadala Brandão, Júlia bobato Ramos de Almeida, Laura Souza de Jesus, Letícia Barroso Luniere, Luiza Fernanda Mendonça Nicolau, Mariana Belo de Almeida, Walace Silva Ataides, Natalia da Silva Ataide
This work is licensed under a Creative Commons Attribution 4.0 International License.
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