IMPACT OF COVID-19 ON PATIENTS WITH NEUTROPENIA FEBRUARY
DOI:
https://doi.org/10.36557/2674-8169.2024v6n8p4661-4672Keywords:
COVID-19, Febrile Neutropenia, Viral Infections.Abstract
COVID-19 has posed significant challenges for patients with febrile neutropenia, a condition characterized by low neutrophil counts and fever, often resulting from chemotherapy treatments. This article aims to conduct a systematic review of the literature on the impact of COVID-19 on patients with febrile neutropenia, following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The research was conducted in the PubMed, SciELO, and BVS databases, covering the last five years (2018-2023). The search strategy included terms such as "COVID-19," "febrile neutropenia," and "viral infections." The results indicate that patients with febrile neutropenia are at increased risk of severe complications and mortality when infected with SARS-CoV-2. The immunosuppression associated with neutropenia compromises the immune response, making these patients more susceptible to secondary infections and worsening of COVID-19. Additionally, the review highlights the need for specific management and treatment protocols for this vulnerable population, including the use of antiviral therapies, prophylactic antibiotics, and rigorous monitoring. It is concluded that COVID-19 exacerbates clinical challenges in patients with febrile neutropenia, requiring multidisciplinary approaches to minimize risks and improve clinical outcomes.
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Copyright (c) 2024 Catharine Garcia Lopes , Guilherme Cristovam Pina , Charbell Guthierry Almeida de Mendonça, Gabriella Batista Centurion de Santa Rosa, Gabriel Camargo Villas Boas Zambrin, Bianca Dantas Vieira, Ana Karolina Gomes, Camila Freitas Barbosa , Jhessyka Burgatti Cardozo, Vanessa Scandolara Loureiro, Luiz Antonio Minguetti Loureiro, Geovanna Porto Inácio
This work is licensed under a Creative Commons Attribution 4.0 International License.
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