Combined Strategies in the Treatment of Inflammatory Bowel Diseases: Clinical and Surgical Approaches

Abstract

This article reviews and discusses combined strategies in the treatment of Inflammatory Bowel Diseases (IBDs), focusing on the integration of clinical and surgical approaches. The integrative literature review covers recent studies exploring the use of biological therapies, such as infliximab and adalimumab, in conjunction with surgical interventions, particularly in patients with Crohn's Disease and Ulcerative Colitis. The findings indicate that combining these strategies can enhance treatment efficacy, especially when tailored to the individual characteristics of patients, such as comorbidities and treatment response. Personalized dosing and therapeutic monitoring are highlighted as essential for optimizing outcomes, while treatment adherence remains a significant challenge. Additionally, the impact of obesity and the potential of Fecal Microbiota Transplantation (FMT) are discussed as important factors in the management of IBDs. The study concludes that integrating clinical and surgical therapies offers a promising approach to treating IBDs, although individualized adaptation for each patient is necessary based on their specific condition and treatment response.