MANAGEMENT OF SEPSIS AND ACUTE INFECTIONS: APPROACH IN SURGICAL PATIENTS
DOI:
https://doi.org/10.36557/2674-8169.2024v6n8p1848-1860Keywords:
Sepsis, Acute Infections, Surgical Patients.Abstract
Introduction: Management of sepsis and acute infections in surgical patients is essential to prevent serious complications. Sepsis, a systemic inflammatory response to an infection, requires early detection and rapid treatment to prevent progression to septic shock. Therefore, measures such as the use of monitoring protocols, immediate administration of antibiotics and strict wound hygiene are crucial. Objective: To provide a comprehensive and practical understanding of how to identify, treat, and prevent sepsis and other acute infections in patients who have undergone surgical procedures. Methodology: The Cochrane, Scielo and Medline databases were used, searching for articles published between 2022 and 2024, in Portuguese or English. Final Considerations: The management of sepsis and acute infections in surgical patients requires a multidisciplinary and immediate approach, as early recognition and rapid use of antimicrobial therapies, along with control of the source of infection, are crucial. Furthermore, hemodynamic management must be personalized, and prevention through prophylaxis protocols and strict infection control is essential.
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Bedawi, Eihab et al. Early Video Assisted Thoracoscopic Surgery (VATS) or Intrapleural Enzyme Therapy (IET) in Pleural Infection – A Feasibility Randomized Controlled Trial (The Third Multicenter Intrapleural Sepsis Trial – MIST-3). *American Journal of Respiratory and Critical Care Medicine*, v. 208, n. 12, p. 1305–1315, 15 dez. 2023.
Gray, A. J. et al. Albumin Versus Balanced Crystalloid for the Early Resuscitation of Sepsis: An Open Parallel-Group Randomized Feasibility Trial. The ABC-Sepsis Trial. *Critical Care Medicine*, 24 jun. 2024.
Hu, X.; Yan, L. A secondary abdominal aorta-duodenal fistula accompanied with acquired Immune Deficiency Syndrome presented with recurrent sepsis: a case report. *BMC Infect Dis*, p. 669–669, 2024.
Jorda, A. et al. Fluid management for sepsis-induced hypotension in patients with advanced chronic kidney disease: a secondary analysis of the CLOVERS trial. *Critical Care*, v. 28, n. 1, 11 jul. 2024.
Mansilla-Roselló, A. et al. A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensive care unit. *Journal of Pineal Research*, v. 74, n. 2, 2 dez. 2022.
Munroe, E. S. et al. Understanding How Clinicians Personalize Fluid and Vasopressor Decisions in Early Sepsis Management. *JAMA Network Open*, v. 7, n. 4, p. e247480–e247480, 19 abr. 2024.
Persson, I. et al. Early prediction of sepsis in intensive care patients using the machine learning algorithm NAVOY® Sepsis, a prospective randomized clinical validation study. *Journal of Critical Care*, v. 80, p. 154400–154400, 1 abr. 2024.
Shehadeh, I. et al. Open or closed abdomen post laparotomy to control severe abdominal sepsis: a survival analysis. *Revista do Colégio Brasileiro de Cirurgiões*, v. 51, 1 jan. 2024.
Silva, C. M. et al. Valor prognóstico da hiperlactatemia em pacientes admitidos com infecção em unidades de terapia intensiva: estudo multicêntrico. *Revista Brasileira de Terapia Intensiva*, v. 34, n. 1, 2022.
Tagar, Esteem et al. Abdominal wound closure in the presence of sepsis: our experience with the use of subcutaneous drain. *Ghana Medical Journal*, v. 58, n. 1, p. 26–33, 25 mar. 2024.
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Copyright (c) 2024 Priscylla Lucena Santos, Marcellus de Lucena Oliveira , Raphael Navarro Aquilino, Matheus Lucena Santos, Leandro Aparecido Irrazabal, Marcus Vinícius Cordeiro Costa , Luana Vasconcellos Mendonça Schiphorst , Anelise Molinari Parreira , Kadyja Ferraz de Melo, Daniel Felipe Nobre Castiel , Pedro Henrique Barroso Aguiar, Taina Santos Oliveira, Danielli Xavier Tamietti Durães

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