Lip Fillers with Greater Complications of Persistent Intermittent Delayed Swelling (PIDS): A Literature Review

Authors

  • Luisa Fernandes Mota São Leopoldo Mandic (SLM campinas) / Medicina
  • Clara de Oliveira Nalini Martins Universidade Nove de Julho (UNINOVE) / Medicina
  • Rafaela Andrade Almeida Drumond São Leopoldo mandic (Campinas)/ medicina
  • Eduarda Gonçalves Ferreira São Leopolfo Mandic (Campinas) Medicina
  • Laura Winter São Leopoldo Mandic (SLM Campinas) / Medicina

DOI:

https://doi.org/10.36557/2674-8169.2024v6n8p1284-1298

Keywords:

Late complications; Hyaluronic acid; Inflammatory reactions.

Abstract

​The evaluation of the efficacy and safety of lip fillers, particularly concerning complications such as Persistent Intermittent Delayed Swelling (PIDS), requires a comprehensive approach that considers both the aesthetic benefits and the potential risks associated with these procedures. A detailed analysis of risk factors and techniques used is essential to ensure safe and satisfactory outcomes while minimizing any potential adverse effects on patient health.

​The efficacy of lip fillers is measured by their ability to achieve the desired aesthetic results while preventing severe complications like PIDS, which can lead to prolonged discomfort, facial asymmetry, and the need for additional treatments. New techniques and formulations are constantly being developed to enhance the safety and outcomes of fillers, providing a better quality of life for patients. Clinical and laboratory studies are crucial to testing these aspects, ensuring that new approaches deliver the expected benefits without compromising patient health.

​The safety of treatments with lip fillers is a constant concern. Products such as hyaluronic acid and other materials have been the subject of studies to assess their potential to cause adverse reactions, both immediate and delayed, including PIDS. Continuous research and regulatory review are crucial to ensure that products available on the market are safe for long-term use, especially given the increasing popularity of these aesthetic procedures.

​Beyond efficacy and safety for patients, the sustainability and viability of lip fillers are also important considerations. Safe administration methods, post-procedure care, and proper management of possible complications are essential factors. Therefore, there is a growing movement to develop techniques that are safe, effective, and accessible for all patients seeking to enhance their facial appearance.

​In summary, evaluating the efficacy and safety of lip fillers, particularly in the context of complications like PIDS, is a complex process that involves multiple facets, from risk prevention and material safety to the sustainability of applied techniques. An integrated and continuous approach to research and development is essential to ensure that lip fillers offer safe and effective aesthetic results, contributing to patient satisfaction and the quality of facial aesthetic services.

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References

BARANSKA-RYBAK, Wiesława et al. Unexpected effects of long-term use of fillers for aesthetic medicine: diagnostic and therapeutic challenges. European Journal of Dermatology, vol. 34, n. 2, p. 203-213, 2024.

BEZERRA, João Victor; VASCONCELOS-SCHAEFER, Luiza. Persistent Intermittent Delayed Swelling (PIDS) caused by Hyaluronic Acid filler after five years: report of late complication. Surgical & Cosmetic Dermatology, vol. 15, e20230259, 2023.

DIWAN, Sudhakar et al. Post COVID-19 inflammatory responses in patients with dermal fillers: a review of clinical cases. Journal of Clinical and Aesthetic Dermatology, vol. 16, n. 1, p. 32-38, 2023.

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NEAMATALLAH, Fatima et al. Risk of complications associated with cosmetic fillers: a meta-analysis. Journal of Dermatological Treatment, vol. 34, n. 1, p. 27-34, 2023.

ROSENDY, Samuel et al. Adverse reactions to soft tissue fillers in aesthetic procedures: a multi-center retrospective analysis. Aesthetic Surgery Journal, vol. 43, n. 4, p. 475-483, 2023.

SCARANO, Antonio et al. Chronic lip edema and pain secondary to lip augmentation procedure: histological, scanning electron microscopy and X-ray microanalysis evaluation. European Review for Medical and Pharmacological Sciences, vol. 27, n. 3 Suppl, p. 147-152, 2023.

TRINH, Tam; McGUIGAN, Matthew; GUPTA, Amit. Advances in understanding the immunological mechanisms underlying complications from dermal fillers. Clinical and Experimental Dermatology, vol. 47, n. 11, p. 1878-1885, 2022.

Published

2024-08-09

How to Cite

Fernandes Mota, L., de Oliveira Nalini Martins, C., Andrade Almeida Drumond , R., Gonçalves Ferreira, E., & Winter , L. (2024). Lip Fillers with Greater Complications of Persistent Intermittent Delayed Swelling (PIDS): A Literature Review. Brazilian Journal of Implantology and Health Sciences, 6(8), 1284–1298. https://doi.org/10.36557/2674-8169.2024v6n8p1284-1298