Management Strategies for Cutaneous Manifestations of Systemic Lupus Erythematosus: A Comprehensive Review
PDF (Português (Brasil))

Keywords

Systemic lupus erythematosus, cutaneous manifestations, management strategies, diagnosis, treatment.

How to Cite

Caruso , L. C., Gutierrez , D. F., Golcman , L. R., Calil , V. A. A., Gadelha , G. C. A., Faria , J. T., Gruska , P. M., Santos , G. F. dos, Leite, G. F., Taparello , I., Orr , M. B., Trein, S., Almeida , L. O. F. de, Duchesqui , M. R., Dias , M. da N., & Santos , I. P. dos. (2024). Management Strategies for Cutaneous Manifestations of Systemic Lupus Erythematosus: A Comprehensive Review. Brazilian Journal of Implantology and Health Sciences, 6(7), 695–711. https://doi.org/10.36557/2674-8169.2024v6n7p695-711

Abstract

Introduction: Cutaneous manifestations of systemic lupus erythematosus (SLE) represent a significant and challenging aspect of this autoimmune disease. This study aims to explore management strategies for these cutaneous manifestations, with the goal of improving understanding and treatment of this complex dermatological condition. Objective: The objective of this study is to analyze management strategies for cutaneous manifestations of SLE, highlighting diagnostic and therapeutic approaches, as well as challenges faced in clinical practice. The intention is to provide a comprehensive overview of available treatment options and identify areas in need of further investigation and development. Methodology: To achieve this objective, a systematic literature review was conducted using specific descriptors related to systemic lupus erythematosus and its cutaneous manifestations. Relevant studies were selected based on pre-defined inclusion criteria, considering their methodological quality and relevance to the topic at hand. Results: Analysis of selected studies revealed a variety of management strategies for cutaneous manifestations of SLE, including topical and systemic treatments, complementary therapies, and preventive measures. Additionally, diagnostic challenges such as overlap with other dermatological conditions, and therapeutic challenges such as the need for more effective treatment options with fewer side effects, were identified. Conclusion: Management of cutaneous manifestations of SLE requires a multidisciplinary and individualized approach, aiming to control disease activity, prevent complications, and improve patients' quality of life. Continuous research and development of new therapies are essential to advance the treatment of this challenging dermatological condition.

 

https://doi.org/10.36557/2674-8169.2024v6n7p695-711
PDF (Português (Brasil))

References

Borba EF, Latorre LC, Brenol JCT, Kayser C, Silva NA da, Zimmermann AF, et al. Consenso de lúpus eritematoso sistêmico. Revista Brasileira de Reumatologia [Internet]. 2008 Aug 1;48(4):196–207. Available from: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042008000400002&nrm=iso&tlng=pt

Galindo CVF, VEIGA RKA. CARACTERÍSTICAS CLÍNICAS E DIAGNÓSTICAS DO LÚPUS ERITEMATOSO SISTÊMICO: UMA REVISÃO. Revista Eletrônica de Farmácia. 2011 Feb 16;7(4).

Lira M, Lazzarin GDB, Narzetti RA, Gazoni VF. LÚPUS ERITEMATOSO SISTÊMICO E SUAS MANIFESTAÇÕES NEURO VASCULARES E CEREBRAIS. Simpósio de Neurociência Clínica e Experimental [Internet]. 2023 Nov 15 [cited 2024 Abril 6]; Available from: https://portaleventos.uffs.edu.br/index.php/SIMPNEURO/article/view/19972

Macedo RM, Garcia T ´Ribeiro, Castanheira EP, Noleto DC, Freitas TVM, Freitas A de A. Lúpus Eritematoso Sistêmico: relação entre os diferentes tratamentos e evolução clínica. Revista de Medicina [Internet]. 2020 Dec 20;99(6):573–80. Available from: https://www.revistas.usp.br/revistadc/article/view/173579

Monticielo O, Roberto De Fraga Brusch L, Carlos J, Brenol T, Krug B, Beatriz C, et al. Consultores: Protocolo Clínico e Diretrizes Terapêuticas 1 METODOLOGIA DE BUSCA E AVALIAÇÃO DA LITERATURA [Internet]. Available from: https://reumatodf.com.br/images/2021/04/formularios/Lupus-Eritematoso-PCDT-Portaria-SAS-MS-no-100-de-7-de-fevereiro-de-2013-retificada-em-22-de-marco-de-2013.pdf

Nascimento M, Oliveira D. LÚPUS ERITEMATOSO SISTÊMICO, UMA REVISÃO DE LITERATURA DAS CARACTERÍSTICAS, DIAGNÓSTICOS E TRATAMENTOS [Internet]. 2011. Available from: https://bdm.unb.br/bitstream/10483/1752/1/2001_M%C3%A1rcioNascimentodeOliveira.pdf

Nazaré K, De Souza Leal W, Fernandes E, Cássio F, Silva S, Da M, et al. LÚPUS ERITEMATOSO SISTÊMICO: MÉTODOS DE DIAGNÓSTICO E ESTRATÉGIAS DE TRATAMENTO SYSTEMIC LUPUS ERYTHEMATOSUS: DIAGNOSTIC METHODS AND TREATMENT STRATEGIES. Brazilian Journal of Surgery and Clinical Research -BJSCR BJSCR [Internet]. 2021;34(3):2317–4404. Available from: https://www.mastereditora.com.br/periodico/20210507_074214.pdf

Renato M, Baaklini, César Emile. Lúpus eritematoso sistêmico. RBM rev bras med [Internet]. 2022;274–85. Available from: https://pesquisa.bvsalud.org/portal/resource/pt/lil-529241

Sales IM, Borges GM, Morais BP, Moreira FB de L, Rocha LCP, Martins LR de S, et al. Lúpus Eritematoso Sistêmico - aspectos epidemiológicos, fisiopatológicos e manejo terapêutico. Brazilian Journal of Health Review [Internet]. 2023 Sep 11;6(5):20242–51. Available from: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/62837/45202

Silva HA de M e, Oliveira AD de, Oliveira CF de, Miranda GM, Oliveira MM de, Novacki RAL, et al. Lúpus Eritematoso Sistêmico: uma revisão atualizada da fisiopatologia ao tratamento / Systemic Lupus Erythematosus: An Up-to-Date Review of Pathophysiology of Treatment. Brazilian Journal of Health Review [Internet]. 2021 Nov 9;4(6):24074–84. Available from: https://brazilianjournals.com/index.php/BJHR/article/view/39175

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2024 Lucas Cabana Caruso , David Flores Gutierrez , Luna Rech Golcman , Vitor Azem Arantes Calil , Gabriel Carvalho Andrade Gadelha , Jaqueline Telles Faria , Paola Marin Gruska , Gabriel Felipe dos Santos , Glenda Ferreira Leite, Isadora Taparello , Manuela Biagi Orr , Sofia Trein, Lucca Oliveira Franklin de Almeida , Mariana Regina Duchesqui , Milena da Nóbrega Dias , Isabella Peixoto dos Santos