Keywords
Depression
Aged
Cognitive Decline
How to Cite
Abstract
Epidemiological and clinical studies have consistently indicated a bidirectional association between dementia and depression in the elderly. As a result, it is necessary to understand the factors associated with the concomitant development of these conditions. Therefore, this work aims to understand the correlations and factors associated with the mutual presence of dementia and depression in the elderly. This article is an Integrative Literature Review methodology, with research carried out in the BVS, PubMed and SciELO databases, using the following descriptors in health sciences: “Dementia”, “Depression”, “Aged” and “Cognitive Decline”, together with the Boolean operator “AND”, observing articles published over the last 5 years in English, Portuguese and Spanish. After the end of the research, 13 articles were selected to form the discussion of this work. There is a strong correlation between the concomitant presence of dementia and depression in the elderly, although the causal relationship between the two conditions is still uncertain. While some studies indicate that depression leads to dementia, others suggest the opposite relationship, and others have not even managed to establish a relationship, merely attesting to the mutual presence of the conditions. Furthermore, sociodemographic factors may influence the correlation between diseases in an uncertain manner. Factors such as advanced age, female gender, cognitive and functional impairment, genetic factors, comorbidities, emotional factors and use of certain psychotropic medications have been associated with the concomitant presence of depression and dementia in the elderly.
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Copyright (c) 2024 David Sammuel Dantas Torres, Fabricio Ricardo Valerio, Caroline Haussman dos Santos, Thiago de Souza Leão Câmara, Sophia Lima Luiz Ramalho França, Soraya Sarmento de Melo, Francis Kleber Pereira Lacerda de Souza, Beatriz Potyguara Wanderley Martins, Maria Clécia Dantas de Freitas, Ana Paula Gonçalves Ramacciotti, Glicio Wellington Ribeiro Lopes, Vaniely Oliveira Ferreira
