IMMUNE THROMBOCYTOPENIA: CURRENT STRATEGIES IN DIAGNOSIS AND TREATMENT

Authors

  • Djosci Coêlho de Sá Júnior Residente em Medicina de Família e Comunidade - Universidade de Gurupi https://orcid.org/0009-0001-3185-2375
  • Samuel Lacerda do Nascimento Universidade Federal do Amazonas
  • Luiz Flávio Ferreira Filho Residência Médica em Medicina de Família e Comunidade pelo Hospital das Clínicas da UFMG. Pós graduando em Psiquiatria pela Faculdade Cenbrap. Pós graduando em Psiquiatria da infância e adolescência e neuropediatria pela FGMED.
  • Amanda Vanessa Bandeira de Araújo Cavalcanti Graduanda em Medicina pela Universidade Estadual de Ciências da Saúde de Alagoas
  • Eduardo Braatz Boniatti Médico pela Universidade do Oeste de Santa Catarina - UNOESC https://orcid.org/0000-0002-3968-9584
  • Cíntia Almeida Ferreira Enfermeira pela Universidade Católica de Salvador - UCSal https://orcid.org/0000-0001-6501-0494
  • Daiane de Lima Abreu Universidade Maurício de Nassau - UNINASSAU
  • Thais Bethania Moreira Cunha Calixto Faculdade de Medicina de Petrópolis - FMP/Unifase
  • Mayara Patrícia Baptista Correia Graduanda em Medicina pela Universidade Federal do Pará
  • Sara Janaina Wibiki Mendes Rodrigues Torres Faculdade de Medicina da Usp - FMUSP
  • Camilla Carvalho de Almeida Universidade Maurício de Nassau - UNINASSAU
  • Júlio César Pinto Vasconcelos Médico pela Faculdade de Ciências Médicas de Campina Grande - UNIFACISA / FCM
  • Mariele Leal Melo Médica pela Universidade Federal de Santa Catarina - UFSC
  • Luísa Mendonça Franco Médica pela Faculdade de Medicina de Petrópolis
  • Renata Ellen Maria de Carvalho Dutra Médica pelo Centro Universitário Maurício de Nassau - UNINASSAU

DOI:

https://doi.org/10.36557/2674-8169.2024v6n5p402-414

Keywords:

Immune Thrombocytopenia, Diagnosis, Treatment.

Abstract

Immune thrombocytopenia is a condition in which the immune system attacks and destroys blood platelets, leading to complications such as excessive bleeding. This review aims to explore current strategies in the diagnosis and treatment of immune thrombocytopenia, aiming to improve the understanding and management of this challenging hematological condition. Objective: The aim of this study is to analyze the diagnostic and therapeutic approach to immune thrombocytopenia, highlighting current trends and knowledge gaps. The methodology involved systematic literature search using health science descriptors and careful selection of relevant studies for analysis.  Methodology: Descriptors such as "Immune Thrombocytopenia," "Pathophysiology," "Diagnosis," and "Treatment" were used in various combinations to identify relevant articles in electronic databases. Inclusion criteria were defined based on relevance to the topic and methodological quality of selected studies. After identifying relevant studies, available diagnostic and therapeutic approaches in clinical practice were analyzed. Results: Analysis of selected studies revealed a variety of diagnostic strategies used, including laboratory tests and imaging. Regarding treatment, therapeutic options such as corticosteroids, intravenous immunoglobulin, and spleen-directed therapies were identified. Additionally, new therapeutic approaches under development, such as targeted biological therapies, were explored as promising alternatives. Conclusion: In conclusion, immune thrombocytopenia represents a significant clinical challenge that requires a multidisciplinary and individualized approach to its management. Understanding underlying mechanisms, early identification of patients at risk, and access to effective treatments are crucial for improving clinical outcomes and patients' quality of life. Continuity of research and medical education are essential to advance knowledge and treatment of this complex hematological condition.

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References

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Published

2024-05-06

How to Cite

Júnior , D. C. de S., Nascimento , S. L. do, Filho , L. F. F., Cavalcanti , A. V. B. de A., Boniatti , E. B., Ferreira , C. A., Abreu , D. de L., Calixto , T. B. M. C., Correia , M. P. B., Torres, S. J. W. M. R., Almeida, C. C. de, Vasconcelos , J. C. P., Melo , M. L., Franco, L. M., & Dutra , R. E. M. de C. (2024). IMMUNE THROMBOCYTOPENIA: CURRENT STRATEGIES IN DIAGNOSIS AND TREATMENT. Brazilian Journal of Implantology and Health Sciences, 6(5), 402–414. https://doi.org/10.36557/2674-8169.2024v6n5p402-414

Issue

Vol. 6 No. 5 (2024): BJIHS QUALIS B3 - FATOR DE IMPACTO SJIF 5.807

Section

Literature Review

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Copyright (c) 2024 Djosci Coêlho de Sá Júnior , Samuel Lacerda do Nascimento , Luiz Flávio Ferreira Filho , Amanda Vanessa Bandeira de Araújo Cavalcanti , Eduardo Braatz Boniatti , Cíntia Almeida Ferreira , Daiane de Lima Abreu , Thais Bethania Moreira Cunha Calixto , Mayara Patrícia Baptista Correia , Sara Janaina Wibiki Mendes Rodrigues Torres, Camilla Carvalho de Almeida, Júlio César Pinto Vasconcelos , Mariele Leal Melo , Luísa Mendonça Franco, Renata Ellen Maria de Carvalho Dutra

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