Determinantes Clínicos e Moleculares da Resposta ao Tratamento Neoadjuvante em Câncer de Mama: Uma Revisão Sistemática

José Lucas Moura Vasconcelos; Anne Louyse Gomes Souza; Braz Martins  Neto; Camilla Barreto Passos; Carine Cecconello; Célio Silva Filho; Eugênio Alencar Muniz Filho; Julia Maria Prestes Capatto; Júlia Terra Suzano; Karen Simone Fizinus Rodrigues; Karolayne Skiba Lazzari; Layannara Nascimento Santos; Luiz Gabriel Negro Vaz Seffair; Marcela Vilela de  Lima; Menderson Augusto Gadelha Cavalcante; Monique Evelyn Alves de Queiroz; Nara Lis Freire Benigno; Priscila Coti Lewin; Raphaela Guimarães Fiel; Renan Brezinski Coradin; Roberta Calumby Barretto de Macedo; Roberta Rodrigues de Lima

doi:10.36557/2674-8169.2024v6n2p1815-1822

Clinical and Molecular Determinants of Neoadjuvant Treatment Response in Breast Cancer: A Systematic Review

Authors

José Lucas Moura Vasconcelos UniFG Guanambi
Anne Louyse Gomes Souza Universidade Tiradentes - UNIT https://orcid.org/0009-0009-5974-3144
Braz Martins Neto Universidade de Cuiabá - UNIC https://orcid.org/0000-0002-3986-3781
Camilla Barreto Passos Universidade Tiradentes - UNIT https://orcid.org/0009-0003-2641-4578
Carine Cecconello Unochapecó https://orcid.org/0000-0002-7604-4283
Célio Silva Filho FACULDADE DAS AMÉRICAS - FAM https://orcid.org/0009-0006-5837-1180
Eugênio Alencar Muniz Filho Faculdade Pernambucana de Saúde - FPS https://orcid.org/0009-0009-3341-1395
Julia Maria Prestes Capatto Universidade de Cuiabá - UNIC https://orcid.org/0009-0003-8055-7086
Júlia Terra Suzano Centro Universitário Municipal de Franca - UNIFACEF https://orcid.org/0009-0009-9136-3723
Karen Simone Fizinus Rodrigues Universidade Paranaense - UNIPAR https://orcid.org/0009-0007-2502-7989
Karolayne Skiba Lazzari Universidade Paranaense - UNIPAR https://orcid.org/0009-0006-6356-1966
Layannara Nascimento Santos Universidade de Cuiabá - UNIC https://orcid.org/0009-0006-2935-5931
Luiz Gabriel Negro Vaz Seffair Universidade Nilton Lins https://orcid.org/0009-0008-7236-8134
Marcela Vilela de Lima Faculdade de Medicina Municipal de Franca https://orcid.org/0009-0006-3447-912X
Menderson Augusto Gadelha Cavalcante Universidade Nilton Lins https://orcid.org/0009-0009-8620-6643
Monique Evelyn Alves de Queiroz Universidade Metropolitana da Amazônia - UNIFAMAZ https://orcid.org/0009-0001-0373-8479
Nara Lis Freire Benigno Faculdade de Medicina de Olinda - FMO https://orcid.org/0009-0007-8207-3658
Priscila Coti Lewin Universidade Anhembi Morumbi - UAM https://orcid.org/0009-0002-0517-9516
Raphaela Guimarães Fiel Universidade Tiradentes - UNIT https://orcid.org/0009-0008-0855-7344
Renan Brezinski Coradin Universidade Paranaense - UNIPAR https://orcid.org/0009-0000-6437-0623
Roberta Calumby Barretto de Macedo Universidade Tiradentes - UNIT https://orcid.org/0009-0004-4517-3076
Roberta Rodrigues de Lima Faminas Muriaé https://orcid.org/0009-0001-9490-1509

DOI:

https://doi.org/10.36557/2674-8169.2024v6n2p1815-1822

Keywords:

breast cancer, neoadjuvant treatment

Abstract

This article presents a systematic review of the clinical and molecular determinants of response to neoadjuvant treatment in patients with breast cancer. Searches were conducted in scientific databases to identify relevant studies investigating factors associated with response to neoadjuvant treatment. The results highlighted the importance of tumor molecular subtype, patient clinical characteristics, and biomarker expression in predicting treatment response. Understanding these determinants can provide valuable insights for clinical practice and guide future research on breast cancer management.

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References

Cortazar, P., Zhang, L., Untch, M., et al. (2014). Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis. Lancet, 384(9938), 164-172.

Nichols, H. B., Schoemaker, M. J., Wright, L. B., et al. (2018). Association of Body Mass Index and Age With Subsequent Breast Cancer Risk in Premenopausal Women. JAMA Oncology, 4(6), e181771.

Odedina, F. T., Bray, F., Ferlay, J., et al. (2019). Breast Cancer Statistics, 2019. CA: A Cancer Journal for Clinicians, 69(6), 438-451.

Sung, H., Ferlay, J., Siegel, R. L., et al. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249.

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Published

2024-02-20

How to Cite

Vasconcelos, J. L. M., Souza, A. L. G., Neto , B. M., Passos, C. B., Cecconello , C., Filho , C. S., Filho, E. A. M., Capatto, J. M. P., Suzano , J. T., Rodrigues, K. S. F., Lazzari, K. S., Santos , L. N., Seffair , L. G. N. V., Lima , M. V. de, Cavalcante, M. A. G., Queiroz , M. E. A. de, Benigno , N. L. F., Lewin, P. C., Fiel, R. G., Coradin , R. B., Macedo, R. C. B. de, & Lima , R. R. de. (2024). Clinical and Molecular Determinants of Neoadjuvant Treatment Response in Breast Cancer: A Systematic Review. Brazilian Journal of Implantology and Health Sciences, 6(2), 1815–1822. https://doi.org/10.36557/2674-8169.2024v6n2p1815-1822

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Issue

Vol. 6 No. 2 (2024): BJIHS QUALIS B3

Section

Systematic Review

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Copyright (c) 2024 José Lucas Moura Vasconcelos, Anne Louyse Gomes Souza, Braz Martins Neto , Camilla Barreto Passos, Carine Cecconello , Célio Silva Filho , Eugênio Alencar Muniz Filho, Julia Maria Prestes Capatto, Júlia Terra Suzano , Karen Simone Fizinus Rodrigues, Karolayne Skiba Lazzari, Layannara Nascimento Santos , Luiz Gabriel Negro Vaz Seffair , Marcela Vilela de Lima , Menderson Augusto Gadelha Cavalcante, Monique Evelyn Alves de Queiroz , Nara Lis Freire Benigno , Priscila Coti Lewin, Raphaela Guimarães Fiel, Renan Brezinski Coradin , Roberta Calumby Barretto de Macedo, Roberta Rodrigues de Lima