Abstract
This article presents a systematic review of the clinical and molecular determinants of response to neoadjuvant treatment in patients with breast cancer. Searches were conducted in scientific databases to identify relevant studies investigating factors associated with response to neoadjuvant treatment. The results highlighted the importance of tumor molecular subtype, patient clinical characteristics, and biomarker expression in predicting treatment response. Understanding these determinants can provide valuable insights for clinical practice and guide future research on breast cancer management.
References
Cortazar, P., Zhang, L., Untch, M., et al. (2014). Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis. Lancet, 384(9938), 164-172.
Nichols, H. B., Schoemaker, M. J., Wright, L. B., et al. (2018). Association of Body Mass Index and Age With Subsequent Breast Cancer Risk in Premenopausal Women. JAMA Oncology, 4(6), e181771.
Odedina, F. T., Bray, F., Ferlay, J., et al. (2019). Breast Cancer Statistics, 2019. CA: A Cancer Journal for Clinicians, 69(6), 438-451.
Sung, H., Ferlay, J., Siegel, R. L., et al. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2024 José Lucas Moura Vasconcelos, Anne Louyse Gomes Souza, Braz Martins Neto , Camilla Barreto Passos, Carine Cecconello , Célio Silva Filho , Eugênio Alencar Muniz Filho, Julia Maria Prestes Capatto, Júlia Terra Suzano , Karen Simone Fizinus Rodrigues, Karolayne Skiba Lazzari, Layannara Nascimento Santos , Luiz Gabriel Negro Vaz Seffair , Marcela Vilela de Lima , Menderson Augusto Gadelha Cavalcante, Monique Evelyn Alves de Queiroz , Nara Lis Freire Benigno , Priscila Coti Lewin, Raphaela Guimarães Fiel, Renan Brezinski Coradin , Roberta Calumby Barretto de Macedo, Roberta Rodrigues de Lima