Keywords
How to Cite
Abstract
Introduction: Peripheral Arterial Disease, characterized by the obstruction or narrowing of arteries that supply blood to the extremities, is a global health issue that can lead to significant complications if not properly identified and treated. In the Brazilian context, the specific prevalence and epidemiology of this condition require a thorough analysis to guide effective prevention and intervention strategies.
Methodology: The methodology employed for this systematic review followed a structured protocol. Initially, a search was conducted in the PUBMED database using specific MESH terms, including "Brazil," "Peripheral Arterial Disease," "prevalence," and "Epidemiology." The search was restricted to the period from 2021 to 2023, with the inclusion criteria limited to full-text articles.
Result: It is important to note that the prevalence of Peripheral Arterial Disease significantly increases with age, emphasizing the importance of awareness and preventive interventions in more susceptible populations. Education and health promotion strategies targeting the modification of risk behaviors, such as smoking and diabetes control, are crucial.
Conclusion: The complexity of peripheral arterial disease goes beyond local symptoms, extending to an intrinsic association with a higher risk of severe cardiovascular events, such as myocardial infarction and stroke.
References
Kaplovitch E, Eikelboom JW, Dyal L, Aboyans V, Abola MT, Verhamme P, Avezum A, Fox KAA, Berkowitz SD, Bangdiwala SI, Yusuf S, Anand SS. Rivaroxaban and Aspirin in Patients With Symptomatic Lower Extremity Peripheral Artery Disease: A Subanalysis of the COMPASS Randomized Clinical Trial. JAMA Cardiol. 2021 Jan 1;6(1):21-29. doi: 10.1001/jamacardio.2020.4390. Erratum in: JAMA Cardiol. 2021 Feb 1;6(2):246. PMID: 32997098; PMCID: PMC7527938. Disponível: https://pubmed.ncbi.nlm.nih.gov/32997098/
Eikelboom JW, Bosch J, Connolly SJ, Tyrwitt J, Fox KAA, Muehlhofer E, Neumann C, Tasto C, Bangdiwala SI, Diaz R, Alings M, Dagenais GR, Leong DP, Lonn EM, Avezum A, Piegas LS, Widimsky P, Parkhomenko AN, Bhatt DL, Branch KRH, Probstfield JL, Lopez-Jaramillo P, Rydén L, Pogosova N, Keltai K, Keltai M, Ertl G, Stoerk S, Dans AL, Lanas F, Liang Y, Zhu J, Torp-Pedersen C, Maggioni AP, Commerford PJ, Guzik TJ, Vanassche T, Verhamme P, O'Donnell M, Tonkin AM, Varigos JD, Vinereanu D, Felix C, Kim JH, Ibrahim KS, Lewis BS, Metsarinne KP, Aboyans V, Steg PG, Hori M, Kakkar A, Anand SS, Lamy A, Sharma M, Yusuf S. Long-Term Treatment with the Combination of Rivaroxaban and Aspirin in Patients with Chronic Coronary or Peripheral Artery Disease: Outcomes During the Open Label Extension of the COMPASS trial. Eur Heart J Cardiovasc Pharmacother. 2022 Dec 2;8(8):786-795. doi: 10.1093/ehjcvp/pvac023. PMID: 35383832. Disponível: https://pubmed.ncbi.nlm.nih.gov/35383832/
Felício JS, de Melo FTC, Vieira GM, de Aquino VT, de Souza Parente F, da Silva WM, Said NM, da Silva ER, de Souza ACCB, de Oliveira MCNI, de Lemos GN, de Souza ÍJA, de Alcântara AL, de Moraes LV, Abrahão Neto JF, de Queiroz NNM, Mourão NAL, Piani PPF, Oliveira Dos Reis MS, Felício KM. Peripheral arterial disease progression and ankle brachial index: a cohort study with newly diagnosed patients with type 2 diabetes. BMC Cardiovasc Disord. 2022 Jun 27;22(1):294. doi: 10.1186/s12872-022-02722-6. PMID: 35761179; PMCID: PMC9238109. Disponível: https://pubmed.ncbi.nlm.nih.gov/35761179/
Ferreira JMM, Cunha P, Carneiro A, Vila I, Cunha C, Silva C, Longatto-Filho A, Mesquita A, Cotter J, Mansilha A, Correia-Neves M. Sarcopenia as a Prognostic Factor in Peripheral Arterial Disease: Descriptive Review. Ann Vasc Surg. 2021 Jul;74:460-474. doi: 10.1016/j.avsg.2021.01.076. Epub 2021 Feb 5. PMID: 33556522. Disponível: https://pubmed.ncbi.nlm.nih.gov/33556522/
Berkowitz SD, Bauersachs RM, Szarek M, Nehler MR, Debus ES, Patel MR, Anand SS, Capell WH, Hess CN, Hsia J, Leeper NJ, Brasil D, Mátyás L, Diaz R, Brodmann M, Muehlhofer E, Haskell LP, Bonaca MP. Prevention of arterial and venous thrombotic events in symptomatic peripheral arterial disease patients after lower extremity revascularization in the VOYAGER PAD trial: Dual anticoagulant/antiplatelet regimen vs antiplatelet therapy alone. J Thromb Haemost. 2022 May;20(5):1193-1205. doi: 10.1111/jth.15673. Epub 2022 Mar 7. PMID: 35170216; PMCID: PMC9314576. Disponível: https://pubmed.ncbi.nlm.nih.gov/35170216/
Carvalho J, Correia MA, Kanegusuku H, Longano P, Wolosker N, Ritti-Dias RM, Cucato GG. Association between the risk of malnutrition and functional capacity in patients with peripheral arterial disease: A cross-sectional study. PLoS One. 2022 Sep 9;17(9):e0273051. doi: 10.1371/journal.pone.0273051. PMID: 36083948; PMCID: PMC9462727. Disponível: https://pubmed.ncbi.nlm.nih.gov/36083948/
Cardoso CRL, Melo JV, Santos TRM, Leite NC, Salles GF. Traditional and non-traditional risk factors for peripheral artery disease development/progression in patients with type 2 diabetes: the Rio de Janeiro type 2 diabetes cohort study. Cardiovasc Diabetol. 2021 Feb 27;20(1):54. doi: 10.1186/s12933-021-01249-y. PMID: 33639945; PMCID: PMC7912919. Disponível: https://pubmed.ncbi.nlm.nih.gov/33639945/
Mendes-Pinto D, Rodrigues-Machado MDG, Avelar GL, Navarro TP, Dardik A. Arterial stiffness predicts amputation and death in patients with chronic limb-threatening ischemia. J Vasc Surg. 2021 Dec;74(6):2014-2022.e4. doi: 10.1016/j.jvs.2021.05.052. Epub 2021 Jun 26. PMID: 34182034. Disponível: https://pubmed.ncbi.nlm.nih.gov/34182034/
Araújo TP, Borges LGS, Barroso WKS, Brandão AA, Barbosa ECD, Feitosa ADM, Malachias MVB, Mota Gomes M, Amodeo C, Povoa RMDS, Jardim PCBV, Lopes RD, Batista SRR, Vitorino PVO; researchers of Study I RBH. Factors associated with uncontrolled blood pressure in hypertensive Brazilians. J Clin Hypertens (Greenwich). 2022 Jul;24(7):814-824. doi: 10.1111/jch.14501. Epub 2022 Jun 30. PMID: 35770852; PMCID: PMC9278566. Disponível: https://pubmed.ncbi.nlm.nih.gov/35770852/
Wolosker N, da Silva MFA, Leiderman DBD, Stabellini N, Nogueira WA, Szlejf C, Amaro E Jr, Teivelis MP. Lower Limb Revascularization for Peripheral Arterial Disease in 10,951 Procedures over 11 years in a Public Health System: A Descriptive Analysis of the Largest Brazilian City. Ann Vasc Surg. 2021 Jan;70:223-229. doi: 10.1016/j.avsg.2020.07.026. Epub 2020 Aug 8. PMID: 32781262. Disponível: https://pubmed.ncbi.nlm.nih.gov/32781262/
Ritti-Dias RM, Correia MA, Carvalho JF, Braghieri HA, Wolosker N, Cucato GG, Kanegusuku H. Impact of the COVID-19 pandemic on health lifestyle in patients with peripheral artery disease: A cross-sectional study. J Vasc Nurs. 2022 Mar;40(1):54-58. doi: 10.1016/j.jvn.2022.01.001. Epub 2022 Jan 10. PMID: 35287835; PMCID: PMC8743617. Disponível: https://pubmed.ncbi.nlm.nih.gov/35287835/
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2023 Carolina Costa Bertaioli, Lucy Vieira da Silva Lima, Eliab Batista Barros, Ramon Rodrigues de Moura, Lucas Víctor Gomes da Silva, Yan Kaio Barroso de Almeida, Alyce Silva Correia, Ayla Nunes Vieira, Vitor Habib Figueiredo, Caio Franklin Vicente Matias, Bárbara Almeida Nico, Juliana Galvão Barreto Wyatt, Flávia Dias da Silva, Thais Roveta Costa, Pablo Well do Amaral Rego, Marlus Geizer Pereira Lopes, Thiago Dutra Mendonça