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Este artigo revisa a literatura médica sobre a eficácia dos corticosteroides intranasais e tópicos no tratamento da rinossinusite crônica. A busca foi conduzida no PubMed usando os descritores “Nasal Corticosteroids”, “Topical Corticosteroids”, “Chronic Rhinosinusitis”, e “Treatment”. A análise revelou que a administração pré-operatória de corticosteroides sistêmicos é eficaz na redução da inflamação eosinofílica e na melhoria do planejamento cirúrgico, enquanto os corticosteroides tópicos demonstraram benefícios na função olfativa e na redução dos sintomas e tamanho dos pólipos. Além disso, abordagens combinadas e novas alternativas, como o mepolizumabe, mostraram oferecer benefícios adicionais e melhorar a adesão ao tratamento, destacando a necessidade de estratégias integradas para o manejo da rinossinusite crônica refratária.
Referências
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Copyright (c) 2024 Luiz Henrique Santos, Miguel Isaias Lopes Silveira, Giulia Gabrielly de Lima, João Vitor Ferreira Assunção de Araújo, Maria Fernanda da Silva Rodrigues, Débora, Paloma, Vasques, Paula, Fabrícia, Rafaela, Raphael, Maria Laura, Mariana, José, Thayse Velez Belmont de Brito, Nilber Acioli de Almeida Junior, Clara Beatriz Cesário de Oliveira, Amanda Ramalho Rocha