ORAL CAVITY MESENCHYMAL STEM CELLS: ORIGIN, SURFACE MARKERS, AND REGENERATIVE POTENTIAL
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Palavras-chave

Periodontitis
stem cell
Stem cells; Cellular therapy; Dentistry.
Stem cells, Deciduous tooth, Dental pulp, Bone regeneration
Markers

Como Citar

Xisto Braga Cavalcanti, M. F., Matos , Ícaro G. T. P. D., Costa , A. . G. D. A., Brito, G. D. B., Diomede, F., & Maria , D. A. (2025). ORAL CAVITY MESENCHYMAL STEM CELLS: ORIGIN, SURFACE MARKERS, AND REGENERATIVE POTENTIAL. Brazilian Journal of Implantology and Health Sciences, 7(5), 436–477. https://doi.org/10.36557/2674-8169.2025v7n5p436-477

Resumo

Objective:

This review investigated the origin, surface markers, and the regenerative potential of mesenchymal stem cells from the oral cavity.

Background: 

This review addresses the regenerative potential of mesenchymal stem cells (MSCs) from the oral cavity,  including the formation of dental tissues, pulp tissue, and periodontal tissues, and a whole bio-hybrid tooth composed of dentin, cementum, periodontal ligament, and alveolar bone. Teeth sequelae can be caused by cavities, trauma, or infection, leading to endodontic problems, periodontal disease, and tooth loss.

Method: 

This work selected 67 articles revising the literature using PubMed and Google Scholar, these stem cells were separated according to their origin, surface markers, and regenerative potential.

Conclusion:

Although a lot of research and clinical trials have to be done to validate clinical use of this knowledge in humans,  this field is vast and promising, bringing light to new therapies that can solve clinical problems and reformulate dental treatments shortly.

https://doi.org/10.36557/2674-8169.2025v7n5p436-477
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Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

Copyright (c) 2025 Marcos Fernando Xisto Braga Cavalcanti, Ícaro Gabriel Teles Pacheco De Matos , Ala Gustavo De Andrade Costa , Gianny Dominicci Batista Brito, Francesca Diomede, Durvanei Augusto Maria

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