Oral Manifestations and Complications Resulting from Diabetes: An Interdisciplinary Analysis in Health

Autores

  • Marvin Gonçalves Duarte Faculdade de Odontologia do Recife https://orcid.org/0000-0001-7507-925X
  • Pedro Guimarães Sampaio Trajano Dos Santos Faculdade de Odontologia do Recife https://orcid.org/0009-0001-5720-603X
  • Maria Clara Domingues da Silva Faculdade de Odontologia do Recife
  • Manoel Arthur Dias de Oliveira Antonino Faculdade de Odontologia do Recife
  • Rodolfo Scavuzzi Carneiro Cunha Faculdade de Odontologia do Recife
  • Eudoro de Queiroz Marques Filho Faculdade de Odontologia do Recife
  • Paulo Maurício Reis de Melo Júnior Faculdade de Odontologia do Recife
  • Ailton Coelho de Ataíde Filho Faculdade de Odontologia do Recife
  • Rosana Maria Coelho Travassos Universidade de Pernambuco
  • Luciano Barreto Silva Universidade de Pernambuco

DOI:

https://doi.org/10.36557/2674-8169.2025v7n2p2172-2183

Palavras-chave:

Diabetes Mellitus; Mouth Diseases; Oral Manifestations.

Resumo

Objective: This study aims to analyze the oral manifestations and complications of diabetes mellitus, emphasizing their implications in dental practice and the importance of an interdisciplinary healthcare approach to optimize patient management. Materials and methods: To construct this narrative review, a methodological strategy was developed to ensure the inclusion of the most current, relevant, and scientifically validated information on the topic, providing robust and well-supported content. Comprehensive searches were conducted across multiple databases, including DeCs, BVS/BIREME, PROSPERO, SciELO, PubMed Central, ScienceDirect, Web of Science, and The Cochrane Library, complemented by Google Scholar. Results: Diabetes mellitus significantly increases the risk of periodontal disease, with hyperglycemia leading to an exaggerated inflammatory response and periodontal tissue destruction. Xerostomia, linked to salivary gland dysfunction, promotes dental caries and oral candidiasis, while diabetic neuropathy may induce persistent oral burning sensations. Impaired immune response contributes to a higher prevalence of bacterial and fungal infections, including dental abscesses and osteomyelitis. Additionally, delayed wound healing in diabetic patients complicates post-surgical recovery, increasing the risk of secondary infections and treatment failure. These findings underscore the importance of proactive dental management and interdisciplinary healthcare strategies to mitigate oral complications in diabetic individuals. Conclusion: The conclusion effectively squeeze the relationship between diabetes and oral health while emphasizing the importance of an interdisciplinary approach. It highlights key complications such as periodontal disease, infections, and neuropathic alterations, stressing the need for individualized prevention and treatment strategies. Additionally, it underscores the significance of glycemic control and calls for continued research and healthcare collaboration.outcomes of implant surgeries in the future.

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Referências

Al-Aali, K. A., Alqahtani, A. S., Alzaid, A. A., Saad Hamad Almuiel, Alsaloum, M., & Alanazi, K. K. (2023). Efficacy of adjunct photodynamic therapy on Candida growth and oral health quality of life in denture stomatitis patients with type 2 diabetes mellitus wearing implant-retained overdentures: A randomized clinical study. Photodiagnosis and Photodynamic Therapy, 42, 103630–103630. https://doi.org/10.1016/j.pdpdt.2023.103630

Ali, T., Rumnaz, A., Urmi, U. L., Nahar, S., Rana, M., Sultana, F., Iqbal, S., Rahman, M. M., Rahman, N. A. A., Islam, S., & Haque, M. (2021). Type-2 Diabetes Mellitus Individuals Carry Different Periodontal Bacteria. Pesquisa Brasileira Em Odontopediatria E Clínica Integrada, 21. https://doi.org/10.1590/pboci.2021.049

Chávez-Reyes, J., Escárcega-González, C. E., Chavira-Suárez, E., León-Buitimea, A., Vázquez-León, P., Morones-Ramírez, J. R., Villalón, C. M., Quintanar-Stephano, A., & Marichal-Cancino, B. A. (2021). Susceptibility for Some Infectious Diseases in Patients With Diabetes: The Key Role of Glycemia. Frontiers in Public Health, 9(9). https://doi.org/10.3389/fpubh.2021.559595

D’Alessandro, C., Benedetti, A., Di Paolo, A., Giannese, D., & Cupisti, A. (2022). Interactions between Food and Drugs, and Nutritional Status in Renal Patients: A Narrative Review. Nutrients, 14(1), 212. https://doi.org/10.3390/nu14010212

González-Moles, M. Á., & Ramos-García, P. (2021). State of Evidence on Oral Health Problems in Diabetic Patients: A Critical Review of the Literature. Journal of Clinical Medicine, 10(22), 5383. https://doi.org/10.3390/jcm10225383

Jawed, M. 0137, Khan, R. N., Shahid, S. M., & Azhar, A. (2012). Protective Effects of Salivary Factors in Dental Caries in Diabetic Patients of Pakistan. Experimental Diabetes Research, 2012, 1–5. https://doi.org/10.1155/2012/947304

Llambés, F. (2015). Relationship between diabetes and periodontal infection. World Journal of Diabetes, 6(7), 927. https://doi.org/10.4239/wjd.v6.i7.927

Martorano-Fernandes, L., Dornelas-Figueira, L. M., Marcello-Machado, R. M., Silva, R. de B., Magno, M. B., Maia, L. C., Del Bel Cury, A. A., Martorano-Fernandes, L., Dornelas-Figueira, L. M., Marcello-Machado, R. M., Silva, R. de B., Magno, M. B., Maia, L. C., & Del Bel Cury, A. A. (2020). Oral candidiasis and denture stomatitis in diabetic patients: Systematic review and meta-analysis. Brazilian Oral Research, 34. https://doi.org/10.1590/1807-3107bor-2020.vol34.0113

McKenna, S. J. (2006). Dental Management of Patients with Diabetes. Dental Clinics of North America, 50(4), 591–606. https://doi.org/10.1016/j.cden.2006.06.008

Negrini, T. de C., Carlos, I. Z., Duque, C., Caiaffa, K. S., & Arthur, R. A. (2021). Interplay Among the Oral Microbiome, Oral Cavity Conditions, the Host Immune Response, Diabetes Mellitus, and Its Associated-Risk Factors—An Overview. Frontiers in Oral Health, 2. https://doi.org/10.3389/froh.2021.697428

Petropoulou, P., Kalemikerakis, I., Dokoutsidou, E., Evangelou, E., Konstantinidis, T., & Govina, O. (2024). Oral Health Education in Patients with Diabetes: A Systematic Review. Healthcare, 12(9), 898. https://doi.org/10.3390/healthcare12090898

Rohani, B. (2019). Oral manifestations in patients with diabetes mellitus. World Journal of Diabetes, 10(9), 485–489. https://doi.org/10.4239/wjd.v10.i9.485

Sugandh, F. N. U., Chandio, M., Raveena, F. N. U., Kumar, L., Karishma, F. N. U., Khuwaja, S., Memon, U. A., Bai, K., Kashif, M., Varrassi, G., Khatri, M., Kumar, S., Sugandh, F., Chandio, M., Raveena, F. N. U., Kumar, L., Karishma, F. N. U., Khuwaja, S., Memon, U. A., & Bai, K. (2023). Advances in the management of diabetes mellitus: A focus on personalized medicine. Cureus, 15(8), 1–13. https://doi.org/10.7759/cureus.43697

Surlari, Z., Ciurcanu, O. E., Budala, D. G., Butnaru, O., & Luchian, I. (2023). An Update on the Interdisciplinary Dental Care Approach for Geriatric Diabetic Patients. Geriatrics, 8(6), 114. https://doi.org/10.3390/geriatrics8060114

Tan, H. L., & Renton, T. (2020). Burning mouth syndrome: An update. Cephalalgia Reports, 3, 251581632097014. https://doi.org/10.1177/2515816320970143

Volpato Sanitá, P., Teresinha Giampaolo, E., Montenegro Silva, M., Garcia de Oliveira Mima, E., Garcia Ribeiro, D., & Carlos Eduardo Vergani, C. (2011). Candida spp. prevalence in well controlled type 2 diabetic patients with denture stomatitis. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 111(6), 726–733. https://doi.org/10.1016/j.tripleo.2011.02.033

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Publicado

2025-02-24

Como Citar

Gonçalves Duarte, M., Guimarães Sampaio Trajano Dos Santos, P., Domingues da Silva , M. C., Dias de Oliveira Antonino, M. A., Scavuzzi Carneiro Cunha, R., de Queiroz Marques Filho, E., Reis de Melo Júnior, P. M., Coelho de Ataíde Filho, A., Travassos, R. M. C., & Barreto Silva, L. (2025). Oral Manifestations and Complications Resulting from Diabetes: An Interdisciplinary Analysis in Health. Brazilian Journal of Implantology and Health Sciences, 7(2), 2172–2183. https://doi.org/10.36557/2674-8169.2025v7n2p2172-2183