Palavras-chave
Como Citar
Resumo
Este artigo revisa a literatura atual sobre a relação entre transtornos do sono e a evolução da doença hepática gordurosa não alcoólica (DHGNA). A seleção dos artigos foi realizada utilizando as bases de dados PubMed, Scopus e Web of Science, com os termos “Non-Alcoholic Fatty Liver Disease,” “Sleep Disorders,” e “Progression.” A revisão abrange estudos recentes que investigam o impacto de condições como apneia obstrutiva do sono, insônia e distúrbios do ritmo circadiano na progressão da DHGNA. A conclusão aponta que a identificação e o manejo adequado dos transtornos do sono podem contribuir para retardar a evolução da doença hepática, promovendo melhores desfechos clínicos e qualidade de vida para os pacientes.
Referências
BU, L. F. et al. Non-alcoholic fatty liver disease and sleep disorders. World Journal of Hepatology, [S.l.], v. 16, n. 3, p. 304-315, 2024. Disponível em: WJGNet. Acesso em: 31 dez. 2024.
CHALASANI, N. et al. The diagnosis and management of non‐alcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases. Hepatology, [S.l.], v. 67, n. 1, p. 328-357, 2018.
CHEN, Y. L. et al. Obstructive sleep apnea and risk of nonalcoholic fatty liver disease: a population-based cohort study. Journal of Clinical Sleep Medicine, [S.l.], v. 11, n. 10, p. 955-960, 2015.
DALTRO, C. et al. Nonalcoholic fatty liver disease associated with obstructive sleep apnea: just a coincidence?. Obesity Surgery, [S.l.], v. 20, n. 11, p. 1536-1543, 2010. Disponível em: Arca Fiocruz. Acesso em: 31 dez. 2024.
KARIMI, R. et al. Obstructive sleep apnea is associated with liver injury in patients with nonalcoholic fatty liver disease. Liver International, [S.l.], v. 35, n. 3, p. 653-659, 2015.
KAWADA, T.. Insomnia and non-alcoholic fatty liver disease. Journal of Clinical Sleep Medicine, [S.l.], v. 11, n. 10, p. 1121, 2015.
KIM, J. H. et al. Obstructive sleep apnea is associated with non-alcoholic fatty liver disease in non-obese adults. Journal of Gastroenterology and Hepatology, [S.l.], v. 31, n. 3, p. 638-644, 2016.
KOH, K. H. et al. Obstructive sleep apnea is associated with accelerated liver fibrosis in patients with nonalcoholic fatty liver disease. PLOS ONE, [S.l.], v. 15, n. 9, e0239702, 2020.
MUSSO, G. et al. Association of obstructive sleep apnea with the presence and severity of nonalcoholic fatty liver disease: a systematic review and meta-analysis. Obesity Reviews, [S.l.], v. 14, n. 5, p. 417-431, 2013.
SHI, Y. et al. Obstructive sleep apnea in patients with nonalcoholic fatty liver disease: prevalence and association with metabolic biomarkers. PLOS ONE, [S.l.], v. 10, n. 8, e0135869, 2015.
SINGH, H. et al. Sleep apnea and daytime sleepiness are independently associated with fatty liver index in a population-based study. Liver International, [S.l.], v. 33, n. 5, p. 725-733, 2013.
TAN, H. L. et al. Obstructive sleep apnea and fatty liver disease in children and adolescents. Pediatric Research, [S.l.], v. 75, n. 1-2, p. 1-9, 2014.
TARABANIS, C. et al. Obstructive sleep apnea and liver histology in patients with nonalcoholic fatty liver disease: a single center experience. Journal of Clinical Gastroenterology, [S.l.], v. 42, n. 3, p. 306-307, 2008.
UMBRO, I. et al. Association between non-alcoholic fatty liver disease and obstructive sleep apnea. World Journal of Gastroenterology, [S.l.], v. 26, n. 20, p. 2669-2681, 2020. Disponível em: WJGNet. Acesso em: 31 dez. 2024.
VANWAGNER, L. B. et al. Sleep apnea and nonalcoholic fatty liver disease: a population-based study on the association and predictive value of alanine aminotransferase. Journal of Clinical Gastroenterology, [S.l.], v. 45, n. 9, p. 770-776, 2011.
WANG, X. et al. Obstructive sleep apnea and nonalcoholic fatty liver disease: evidence from a meta-analysis of observational studies. Sleep Medicine, [S.l.], v. 16, n. 7, p. 848-856, 2015.
XIONG, Y. et al. Interaction between the systemic immune-inflammation index and trouble sleeping in nonalcoholic fatty liver disease: a cross-sectional study of the NHANES 2005–2018 data. Journal of Health, Population and Nutrition, [S.l.], v. 43, art. 175, 2024. Disponível em:
Journal of Helminthology. Acesso em: 31 dez. 2024.
YOUNOSSI, Z. M. et al. Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes. Hepatology, [S.l.], v. 64, n. 1, p. 73-84, 2016.
ZHANG, X. et al. Obstructive sleep apnea and its impact on liver histology in patients with nonalcoholic fatty liver disease: A multicenter study. Journal of Hepatology, [S.l.], v. 65, n. 6, p. 1141-1148, 2017.
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Copyright (c) 2025 Thiago Henrique de Andrade Barbosa, Raphael Henrique Gomes de Melo, Juliano Infantino Maciel