COMPLICATIONS OF COVID-19 IN THE GESTATIONAL PERIOD: INTEGRATIVE REVIEW
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Keywords

Pregnant women. COVID-19. Complications

How to Cite

Silva, S. G. R., Rocha, R. O., Ribeiro, L. V. S., Vieira, I. S., & Ferreira, J. B. (2023). COMPLICATIONS OF COVID-19 IN THE GESTATIONAL PERIOD: INTEGRATIVE REVIEW. Brazilian Journal of Implantology and Health Sciences, 5(5), 1866–1884. https://doi.org/10.36557/2674-8169.2023v5n5p1866-1884

Abstract

COVID-19 infection showed a high rate of transmission globally, with care profiles that vary from the level of the disease, as in the majority of those infected, to severe cases. Furthermore, SARS-CoV-2 infection during the gestational period predisposes to a greater risk of premature birth and perinatal death, as a result of iatrogenic induction of premature births, in an attempt to save a seriously ill patient, and systemic inflammatory changes affecting the placenta. Therefore, the present study is an integrative review, at an exploratory level and takes a qualitative form of research, on gestational complications caused by SARS-CoV-2 virus infection, in which 14 articles were included, based on search in electronic databases. Patients exposed to or infected by SARS-CoV-2 had a higher incidence of premature birth, cesarean section, need for resuscitation in the delivery room, Apgar score < 7 in the 5th minute, admission to an intensive care unit and jaundice. Furthermore, during the fourth wave (Delta), the length of hospital stays for patients was shown to be the longest, averaging 111 days; the frequency of X-ray-confirmed pneumonia and the need for non-invasive oxygen support were the highest. Thus, it is concluded that it was possible to observe an increasing number of maternal complications and undeveloped neonatal stages in the newborn, such as increased rates of spontaneous abortion, stillbirths, intrauterine growth restriction, maternal death, and childbirth. premature babies, especially those born iatrogenically

https://doi.org/10.36557/2674-8169.2023v5n5p1866-1884
PDF (Português (Brasil))

References

CARRIÓN-NESSI, F. S. et al. Clinical-epidemiological characteristics and maternal-foetal outcomes in pregnant women hospitalised with COVID-19 in Venezuela: a retrospective study.. BMC PregNancy Childbirth, v. 22, n. 1, p. 905, 2022.

COSMA, S. et al. Longitudinal analysis of antibody response following SARS-CoV-2 infection in pregnancy: From the first trimester to delivery. J Reprod Immunol, 2021.

DE ALMEIDA, J. O. et al. COVID-19: fisiopatologia e alvos para intervenção terapêutica. Revista Virtual de Química, v. 12, n. 6, 2020.

FERRUGINI, C. L. P. et al. SARS-CoV-2 infection in pregnant women assisted in a high-risk maternity hospital in Brazil: Clinical aspects and obstetric outcomes. PLoS One, v. 17, n. 3, 2022.

GODOI, A. P. N. et al. Severe Acute Respiratory Syndrome by COVID-19 in pregnant and postpartum women. Rev Bras Saude Mater Infantil, v. 21, n. 2, 2021.

KOBAYASHI, C. D. et al. Adverse Events Related to COVID-19 Vaccines Reported in Pregnant Women in Brazil. Rev Bras Ginecol Obstet, v. 44, n. 9, 2022.

MALE, V. SARS-CoV-2 infection and COVID-19 vaccination in pregnancy. Nat Rev Immunol, v. 22, n. 5, p. 277-282, 2022.

MIHAJLOVIC, S. et al. Four Waves of the COVID-19 Pandemic: Comparison of Clinical and Pregnancy Outcomes. Viruses, v. 14, n. 12, 2022.

MULLINS, E. et al. Pregnancy and neonatal outcomes of COVID-19: The PAN-COVID study. Eur J Obstet Gynecol Reprod Biol, v. 276, p. 161-167, 2022.

OLIVEIRA, W. K. et al. Como o Brasil pode deter a COVID-19. Epidemiol Serv Saúde, v. 29, n. 2, 2020.

ONCEL, M. Y. et al. A multicenter study on epidemiological and clinical characteristics of 125 newborns born to women infected with COVID-19 by Turkish Neonatal Society. Eur J Pediatr, v. 180, n. 3, p. 733-742, 2021.

PROVENZI, L. et al. Hidden pandemic: COVID-19-related stress, SLC6A4 methylation, and infants' temperament at 3 months. Sci Rep, v. 11, n. 1, p. 15658, 2021.

SAGHAZADEH, A.; REZAEI, N. Immune-epidemiological parameters of the novel coronavirus: a perspective Expert Rev Clin Immunol, v. 16, n. 5, 2020.

SANTOS, C. A. D. et al. Maternal and Neonatal Outcomes Associated with Mild COVID-19 Infection in an Obstetric Cohort in Brazil. Am J Trop Med Hyg, v. 107, n. 5, p. 1060-65, 2022.

SHAH, P. S. et al. Infants Born to Mothers Who Were SARS-CoV-2 Positive during Pregnancy and Admitted to Neonatal Intensive Care Unit. Neonatology, v. 119, n. 5, p. 619-628, 2022.

STOCK, S. J. et al. Pregnancy outcomes after SARS-CoV-2 infection in periods dominated by delta and omicron variants in Scotland: a population-based cohort study. Lancet Respir Med, v. 10, n. 12, p. 1129-1136, 2022.

VIZHEH, M. et al. Maternal and Neonatal Outcomes of COVID-19 Infection in Pregnancy. Arch Iran Med, v. 26, n. 1 p. 43-49, 2023.

WANG, H. et al. The association between pregnancy and COVID-19: A systematic review and meta-analysis. Am J Emerg Med, v. 56, p. 188-195, 2022.

XAVIER, J. A. et al. Epidemiologia, fisiopatologia e complicações da COVID-19: uma revisão de literatura. Journal of Infection Control, v. 9, n. 3, 2020.

ZLATKIN, R. et al. Obstetric and perinatal outcomes in parturients with active SARS-CoV-2 infection during labor and delivery: a retrospective cohort study. BMC Pregnancy Childbirth, v. 22, n.1 p. 511, 2022.

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Copyright (c) 2023 Stephanie Gobira Reis Silva, Rafaela Oliveira Rocha, Lívia Vitória Santos Ribeiro, Iandra Silva Vieira, Juliana Barros Ferreira