Abstract
OBJECTIVE: To describe the potential of cannabis in the treatment of Parkinson's disease. METHOD: The research is an integrative review, carried out based on the following guiding question: What are the potential of cannabis in the treatment of Parkinson's disease? The PICO strategy was used to ask this question, where “p” population: People with Parkinson's disease, “I” interest: Assessment of the potential of cannabis in people with Parkinson's disease, and “C” and “O” context: Description of the potential of cannabis in people with Parkinson's disease. An advanced search was used through the Virtual Health Library (VHL), crossing the descriptors using the Boolean operators “AND” and “OR”. RESULTS: Through advanced research, 14 articles were obtained, among these articles, 5 of them make up this research, which resulted in two categories, namely: Parkinson's disease and cannabis; and the use of cannabis in the treatment of Parkinson's disease. CONCLUSION: It is concluded that, despite the few studies on the potential of cannabis in the treatment of Parkinson's disease, it is observed that there was an improvement in the symptoms of the disease such as tremors, sleep and quality of life.
References
BOUGEA, Anastasia et al. Medical cannabis as an alternative therapeutics for Parkinson's disease: Systematic review. Complementary Therapies in Clinical Practice, v. 39, p. 101154, mai. 2020.
COORAY, R.; GUPTA, V.; SUPHIOLGU, C. Current aspects of the endocannabinoid system and targeted THC and CBD phytocannabinoids as potential therapeutics for Parkinson's and Alzheimer's diseases: a review. Molecular Neurobiology, v. 57, n. 11, p. 4878-4890, nov. 2020.
GONZALEZ-USIGLI, Hector A. Doença de Parkinson. Manual MSD. HE UMAE Centro Médico Nacional de Occidente, revisado/corrido em fev. 2024. Disponível em: <https://www.msdmanuals.com/pt-br/profissional/dist%C3%BArbios-neurol%C3%B3gicos/transtornos-de-movimento-e-cerebelares/doen%C3%A7a-de-parkinson>. Acesso em: 27 ago. 2024.
KEANE, Lim; SEE, Yuen-Mei; LEE, Jimmy. A systematic review of the effectiveness of medical cannabis for psychiatric, movement and neurodegenerative disorders. Clinical Psychopharmacology and Neuroscience, p. 301-312, 2017.
LOPES, Carla Tainá de Oliveira. Uso medicinal da cannabis sativa no tratamento do mal de Parkinson. 2021. Monografia (Bacharelado em Farmácia) – Centro Universitário, Paripiranga, 2021.
MORASH, Michael G. et al. Identification of minimum essential therapeutic mixtures from cannabis plant extracts by screening in cell and animal models of Parkinson's disease. Frontiers in Pharmacology, v. 13, p. 907579, 2022.
SANTOS, Cristina Mamédio da Costa; PIMENTA, Cibele Andrucioli de Mattos; NOBRE, Moacyr Roberto Cuce. A estratégia PICO para a construção da pergunta de pesquisa e busca de evidências. Revista Latino-Americana de Enfermagem, v. 15, n. 3, maio/jun. 2007. Disponível em: www.eerp.usp.br/rlae.
SOUZA, Marcela Tavares de; SILVA, Michelly Dias da; CARVALHO, Rachel de. Revisão integrativa: o que é e como fazer. einstein (São Paulo), São Paulo, v. 8, n. 1 Pt 1, p. 102-106, 2010.
SPEZZIA, Sérgio. O emprego da Cannabis medicinal no enfrentamento à doenças / The use of medicinal Cannabis in fighting diseases. Revista de Ciências Médicas (Campinas), v. 31, e225398, 17 fev. 2022.
TIPOS DE REVISÃO DE LITERATURA. Botucatu: Biblioteca Prof. Paulo de Carvalho Mattos, UNESP, 2015.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2024 Tatiana Assis Araújo Silveira, Ítalo Boaventura Mendes Batista, Wainnye Marques Ferreira, Thais Greco Cataldo Maria, Vinícius Bradão Lemes