Keywords
How to Cite
Abstract
Histochemistry and immunohistochemistry are essential in the forensic field, allowing the detailed analysis of biological samples. Histochemistry reveals chemical components in tissues, while immunohistochemistry detects antigens using labeled antibodies. Methodology: A literature review was carried out, selecting 8 sources from June to July 2024 in databases such as Pubmed, Scielo, Google Scholar and books. Results: The research revealed advances in sensitivity and specificity, thanks to the development of new technologies. Histochemistry and immunohistochemistry are crucial in the identification of biomarkers, traumatic injuries, and pathogens in complex samples. Discussion: The continuous evolution of these techniques strengthens forensic investigation, promoting security and justice through technological innovation and multidisciplinary collaboration.
References
BANCROFT, J. D., Layton, Christopher e Survana, Kim S. Bancroft'S Theory And Practice Of Histological Techniques (5th Edition). London : Elsevier, 2001. ISBN-13: 978- 0443064357.
DE-GIORGIO, Fabio et al. Does the Principle of Cost/Benefit Analysis Apply to Forensic Pathology? American Journal Of Forensic Medicine & Pathology, [S.L.], v. 31, n. 3, p. 300, set. 2010. Ovid Technologies (Wolters Kluwer Health). http://dx.doi.org/10.1097/paf.0b013e3181dfc976. Disponível em: https://pubmed.ncbi.nlm.nih.gov/20421777/. Acesso em: 10 mar. 2024.
DE-GIORGIO, Fabio; VETRUGNO, Giuseppe. Is histological examination always necessary to determine a cause of death? Of course it is! Forensic Science, Medicine, And Pathology, [S.L.], v. 10, n. 3, p. 477-478, 1 mar. 2014. Springer Science and Business Media LLC. http://dx.doi.org/10.1007/s12024-014-9543-x. Disponível em: https://link.springer.com/article/10.1007/s12024-014-9543-x. Acesso em: 10 mar. 2024.
FRANCO, M., et al., Patologia. Processos gerais. 5ª edição. São Paulo, Atheneu, 2010. 331p. ilus. ISBN: 978-85-388-0095-8
KUMAR, V., ABBAS, A., FAUSTO, N. Robbins e Cotran – Patologia – Bases Patológicas das Doenças. 8. ed. Rio de Janeiro: Elsevier, 2010;
LANGLOIS, Neil e I et al. The Use of Histology in 638 Coronial Post-Mortem Examinations of Adults: an audit. Medicine, Science And The Law, [S.L.], v. 46, n. 4, p. 310-320, out. 2006. SAGE Publications. http://dx.doi.org/10.1258/rsmmsl.46.4.310. Disponível em: https://pubmed.ncbi.nlm.nih.gov/17191634/. Acesso em: 07 jun. 2024.
RAMOS-VARA, J. A. et al. Technical Aspects of Immunohistochemistry. Veterinary Pathology, [S.L.], v. 42, n. 4, p. 405-426, jul. 2005. SAGE Publications. http://dx.doi.org/10.1354/vp.42-4-405. Disponível em: https://www.researchgate.net/publication/7737166_Technical_Aspects_of_Immunohistochemistry. Acesso em: 03 maio 2024.
WICK, Mark R. et al. The Impact of Diagnostic Immunohistochemistry on Patient Outcomes. Clinics In Laboratory Medicine, [S.L.], v. 19, n. 4, p. 797-814, dez. 1999. Elsevier BV. http://dx.doi.org/10.1016/s0272-2712(18)30091-x. Disponível em: https://www.sciencedirect.com/science/article/abs/pii/S027227121830091X. Acesso em: 22 abr. 2024.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2024 Daniel José Resende Saggin , Andressa Pontello, Amanda Caroline Bogo Piccinin , José Ignacio Aiquel Bellolio