Liver Surgery and Encephalopathy: Analysis of Neuropsychiatric Effects

Authors

  • Allison Gonçalves Silva Dutra Costa Médico pela Universidade de Taubaté (UNITAU)
  • Janderson de Castro e Silva Médico pela Universidade Federal de Roraima (UFRR)
  • Gabriela Vargas Carneiro Médica pelo Centro Universitário São Lucas de Porto Velho
  • Marcel Pietro Miranda da Silva Médico pela Universidade Federal do Pará (UFPA)
  • Natalia Roquette Giachetto Médica pela Universidade Brasil - Fernandopolis/Sp
  • Iago Pordeus Casimiro Médico pelo Centro Universitário Facisa (Unifacisa)
  • Clara Vidal Barros Médica pelo Centro Universitário Facisa (Unifacisa)
  • Leandro Barroso Barbosa Médico pela Faculdade Integral Diferencial - Facid
  • Pedro Henrique Silva Fernandes Médico pela Universidade Federal de Roraima (UFRR)
  • Estevão dos Santos Diniz Médico pela Universidade Federal de Alfenas (UNIFAL)
  • Thiago Venicius Silva Duarte Acadêmico de Medicina pelo Centro Universitário de João Pessoa (UNIPÊ)
  • Tulio Saltarello Médico pela Fundação Educacional do Município de Assis (FEMA)
  • Camilla Cristina Alves Ribeiro Médica pelo Centro Universitário UniREDENTOR

DOI:

https://doi.org/10.36557/2674-8169.2024v6n7p1407-14021

Keywords:

Liver Surgery, Encephalopathy, Neuropsychiatry.

Abstract

Introduction: Liver surgery and hepatic encephalopathy (HE) are closely linked, with HE representing a significant neuropsychiatric complication resulting from liver dysfunction. During surgical procedures on the liver, the accumulation of toxins, especially ammonia, can worsen HE symptoms, which range from mental confusion to coma. This review focuses on understanding the neuropsychiatric effects of liver surgery and developing management strategies to improve clinical outcomes for affected patients. Objective: To investigate how surgical procedures on the liver contribute to the development or worsening of hepatic encephalopathy. Methodology: The Cochrane, Scielo and Medline databases were used, searching for articles published between 2020 and 2024, in Portuguese or English. Final Considerations: Liver surgery can intensify hepatic encephalopathy (HE) due to the accumulation of neuroactive toxins, such as ammonia. As a result, patients with advanced cirrhosis are particularly susceptible. Therefore, a multidisciplinary approach, including the use of interventions such as lactulose and rifaximin, is crucial to minimize these effects and improve patients' quality of life.

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Published

2024-07-15

How to Cite

Costa , A. G. S. D., Silva, J. de C. e, Carneiro, G. V., Silva, M. P. M. da, Giachetto, N. R., Casimiro, I. P., Barros, C. V., Barbosa, L. B., Fernandes , P. H. S., Diniz , E. dos S., Duarte , T. V. S., Saltarello , T., & Ribeiro, C. C. A. (2024). Liver Surgery and Encephalopathy: Analysis of Neuropsychiatric Effects. Brazilian Journal of Implantology and Health Sciences, 6(7), 1407–14021. https://doi.org/10.36557/2674-8169.2024v6n7p1407-14021