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Abstract
Platelets are known for their role in hemostasis, where they help prevent blood loss at sites of vascular injury. To do this, they adhere, aggregate, and form a procoagulant surface leading to thrombin generation and fibrin formation. Platelets also release substances that promote tissue repair and influence the reactivity of vascular cells and other blood cells in angiogenesis and inflammation. They contain storage pools of growth factors as well as cytokines. Platelet-rich plasma (PRP) was first developed in the mid-1990s, with widespread use not only in dentistry, but also in many areas of medicine, including maxillofacial surgery, orthopedic surgery, and aesthetic medicine. In recent years, PRP has been extensively investigated in regenerative dentistry. It contains growth factors that influence wound healing, so it can contribute a lot to tissue repair. In surgery, PRP reduces bleeding while improving soft tissue healing and bone regeneration.
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Copyright (c) 2023 Victor Diogo da Silva Quaresma , Auanny Vitoria Gomes Alfaia, Mário da Costa de Oliveira , Pedro Paulo Oliveira Ramos, Erika de Nazaré Sales de Miranda Carvalho , Andressa Da Silva Dos Santos , Elaine Veiga de Souza , Talita Rode Ruas Gouthier de Oliveira , Marina Corrêa Costa , Kaique Dlucas Souza Leite Giroux , Ivanildo Mota Alves , José Ivo Antero Junior