MELANOMA: A COMPREHENSIVE ANALYSIS

Authors

  • Natália da Silva Barcala Graduandos em Medicina da Universidade de Marília
  • Felipe Narracci Graduandos em Medicina da Universidade de Marília
  • Gabriel Martins Perillo Graduandos em Medicina da Universidade de Marília
  • Júlia Cauneto Banheti Corredato Graduandos em Medicina da Universidade de Marília
  • Lilian Mariano Fonsatti Graduandos em Medicina da Universidade de Marília
  • Francielli Elaine de Araújo Sampaio Graduandos em Medicina da Universidade de Marília
  • Lorraine da Rosa Bueno Graduandos em Medicina da Universidade de Marília
  • Luiz Eduardo Gomes de Britto Granduandos em Medicina do Centro Universitário IMEPAC
  • Ana Laura Macias Castilhos Granduandos em Medicina da FACERES
  • Sabrina Picin Domingues Granduandos em Medicina da FACERES
  • Ágatha Ianka da Silva Ataides Graduanda em Medicina da Universidade de Rio Verde
  • Bianca Vilela Nascimento Médica pela Universidade de Rio Verde
  • Vitória Mendonça Rodrigues Graduanda em Medicina da UniCerrado
  • Ronaldo Rogério Péres Júnior Graduando em medicina da Universidade Federal de Goiás - Campus Jataí
  • Kamilla Ferreira Paulik Graduanda em medicina da Universidade Federal de Goiás - Campus Jataí
  • Ana Julia Koehler Guedes Coelho Graduanda em Medicina da Pontifícia Universidade Católica de Goiás

DOI:

https://doi.org/10.36557/2674-8169.2023v5n5p4856-4869%20

Keywords:

Melanoma, Skin Neoplasia, Treatment.

Abstract

Melanoma is a malignant cutaneous neoplasm originating in melanocytes, cells responsible for melanin production. This type of skin cancer has the ability to rapidly spread to other organs, potentially leading to serious complications. Dermoscopy, cutaneous biopsy, and positron emission tomography are essential techniques for early diagnosis and staging of melanoma. The treatment of melanoma involves a multidisciplinary approach, incorporating surgery, immunotherapy, targeted therapy, and radiotherapy, depending on the extent of the disease. Notable advancements include immune checkpoint inhibitors such as ipilimumab and pembrolizumab, which have demonstrated significant efficacy in advanced melanomas. Melanoma prevention is grounded in awareness of risk factors, such as excessive sun exposure, and dermatological screening programs in high-risk populations. Molecular understanding of melanoma, including mutations in genes like BRAF, has contributed to more personalized treatment strategies. In summary, melanoma poses a significant clinical challenge, requiring an integrated approach that spans from advanced diagnostic techniques to innovative therapies, with a focus on prevention and awareness.

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References

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Published

2023-12-08

How to Cite

Barcala , N. da S., Narracci , F., Perillo , G. M., Corredato , J. C. B., Fonsatti , L. M., Sampaio , F. E. de A., Bueno, L. da R., Britto , L. E. G. de, Castilhos , A. L. M., Domingues , S. P., Ataides , Ágatha I. da S., Nascimento , B. V., Rodrigues, V. M., Péres Júnior, R. R., Paulik , K. F., & Coelho, A. J. K. G. (2023). MELANOMA: A COMPREHENSIVE ANALYSIS. Brazilian Journal of Implantology and Health Sciences, 5(5), 4856–4869. https://doi.org/10.36557/2674-8169.2023v5n5p4856-4869

Issue

Section

Literature Review