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Esta revisão integrativa analisa a associação entre a suplementação de ácido fólico durante a gravidez e o risco de Transtorno do Espectro do Autismo (TEA) em crianças. A busca incluiu artigos publicados na última década, resultando na seleção de oito estudos epidemiológicos e clínicos relevantes. Os resultados indicam uma tendência consistente de que a suplementação de ácido fólico, tanto antes quanto durante a gravidez, está associada a um menor risco de TEA na prole. No entanto, algumas variações foram observadas em relação ao momento e à duração da suplementação, bem como em diferentes populações estudadas. Esta revisão destaca a importância da suplementação de ácido fólico como uma possível medida preventiva para o TEA e ressalta a necessidade de mais pesquisas para elucidar completamente essa relação e suas implicações clínicas.
Referências
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Copyright (c) 2024 Ana Eliza Riola Chemin, Kerol Martiniano Porcelli, José Eduardo Felipe Souza dos Santos, Alana Sales Guimarães, Angelica Rodrigues Mendes Medeiros, Gabriel de Moura Lima, Lana Nicolle Gomes Bernardo Saraiva, Maria Julia Gomes Ferreira Santos, Maria Vitória Lopes Cordeiro, Rafael Leituga de Carvalho Cavalcante, Ariane Abreu Tsutsumi, Marina Silva Prado