Epidemiological Profile of Live Births with Spina Bifida in Northeast Brazil from 2012 to 2021.
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Keywords

Espinha Bífida, Nascidos Vivos, Nordeste, Brasil.

How to Cite

Barros, E. B., Lins, M. L. N., Yamada, L. S., Silva, P. R. C. da, Silva, R. S. da, Borges, I. M. C., Santos, A. L. R. D., Oliveira, L. M. F. de, Dipanda, S. K., Rego, T. E. do, Verçosa, T. A. S. M., & Barreto, V. L. A. (2023). Epidemiological Profile of Live Births with Spina Bifida in Northeast Brazil from 2012 to 2021. Brazilian Journal of Implantology and Health Sciences, 5(5), 2709–2718. https://doi.org/10.36557/2674-8169.2023v5n5p2709-2718

Abstract

Objective: To develop an epidemiological study of live births with Spina Bifida in the Northeast of Brazil from 2012 to 2021.

Methodology: This study analyzes cases of Spina Bifida in live births in Brazil (2012-2021) using data from SINASC/DATASUS. The aim is to understand the occurrence and distribution of the condition to guide prevention and management strategies. To support the study, specific descriptors were searched in the PUBMED and BVS databases. The research aims to provide valuable insights into Spina Bifida in the context of Northeast Brazil.

Results: From 2012 to 2021, there were 1776 live births with Spina Bifida in the Northeast of Brazil, with 2021 registering the highest number of cases and 2012 the lowest. The highest prevalence occurred in 2021 (0.00027%), and the lowest in 2012 (0.00016%). The average was 0.024 live births with Spina Bifida per 1 live birth. Pernambuco stood out with 26.18% (n = 26.18%) of cases, while Piauí recorded the lowest number, 3.2% (n = 58). The predominant gender among live births with Spina Bifida was male at 51.85% (n = 921). In terms of ethnicity, there was a significant prevalence of mixed-race individuals, accounting for 74.04% (n = 1315). Regarding maternal age, the majority fell within the 20 to 24 age group at 24.32% (n = 432).

Conclusion: Pernambuco had the highest percentage of cases at 26.18%, while Piauí had the lowest rates at 3.2%. Male gender predominated (51.85%), as did mixed-race ethnicity (74.04%) and maternal age in the 20 to 24 age group (24.32%).

 

https://doi.org/10.36557/2674-8169.2023v5n5p2709-2718
PDF (Português (Brasil))

References

Yiğit H, Güler H, Yılmaz H, Gümü ÜÖ, Karaman ZF, Güneş T. Effect of cervical and lumbosacral spina bifida cystica on volumes of intracranial structures in children. Childs Nerv Syst. 2023 Sep 12. doi: 10.1007/s00381-023-06153-2. Epub ahead of print. PMID: 37698650. Disponível: https://pubmed.ncbi.nlm.nih.gov/37698650/.

Chen FC, Gerhardt J, Entezami M, Chaoui R, Henrich W. Detection of Spina Bifida by First Trimester Screening - Results of the Prospective Multicenter Berlin IT-Study. Ultraschall Med. 2017 Apr;38(2):151-157. English. doi: 10.1055/s-0034-1399483. Epub 2015 Apr 14. PMID: 25876171. Disponível: https://pubmed.ncbi.nlm.nih.gov/25876171/.

Micu R, Chicea AL, Bratu DG, Nita P, Nemeti G, Chicea R. Ultrasound and magnetic resonance imaging in the prenatal diagnosis of open spina bifida. Med Ultrason. 2018 May 2;20(2):221-227. doi: 10.11152/mu-1325. PMID: 29730690. Disponível: https://pubmed.ncbi.nlm.nih.gov/29730690/.

Wang HH, Wiener JS, Ross SS, Routh JC. Emergent care patterns in patients with spina bifida: a case-control study. J Urol. 2015 Jan;193(1):268-73. doi: 10.1016/j.juro.2014.06.085. Epub 2014 Jul 9. PMID: 25016137; PMCID: PMC4379115. Disponível: https://pubmed.ncbi.nlm.nih.gov/25016137/

Smith GM, Krynska B. Myelomeningocele: How we can improve the assessment of the most severe form of spina bifida. Brain Res. 2015 Sep 4;1619:84-90. doi: 10.1016/j.brainres.2014.11.053. Epub 2014 Dec 9. PMID: 25498106. Disponível: https://pubmed.ncbi.nlm.nih.gov/25498106/

Acuna J, Lau G, Rad S, Kim M, Gornbein J, Zoppi M, Monni G, Rotmensch S, Solt I. First trimester supratentorial and infratentorial abnormalities in fetuses with open spina bifida. J Matern Fetal Neonatal Med. 2021 Jul;34(13):2159-2165. doi: 10.1080/14767058.2019.1659772. Epub 2019 Sep 4. PMID: 31438742. Disponível: https://pubmed.ncbi.nlm.nih.gov/31438742/.

Trigo L, Eixarch E, Bottura I, Dalaqua M, Barbosa AA, De Catte L, Demaerel P, Dymarkowski S, Deprest J, Lapa DA, Aertsen M, Gratacos E. Prevalence of supratentorial anomalies assessed by magnetic resonance imaging in fetuses with open spina bifida. Ultrasound Obstet Gynecol. 2022 Jun;59(6):804-812. doi: 10.1002/uog.23761. PMID: 34396624. Disponível: https://pubmed.ncbi.nlm.nih.gov/34396624/.

Joyeux L, De Bie F, Danzer E, Russo FM, Javaux A, Peralta CFA, De Salles AAF, Pastuszka A, Olejek A, Van Mieghem T, De Coppi P, Moldenhauer J, Whitehead WE, Belfort MA, Lapa DA, Acacio GL, Devlieger R, Hirose S, Farmer DL, Van Calenbergh F, Adzick NS, Johnson MP, Deprest J. Learning curves of open and endoscopic fetal spina bifida closure: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2020 Jun;55(6):730-739. doi: 10.1002/uog.20389. PMID: 31273862. Disponível: https://pubmed.ncbi.nlm.nih.gov/31273862/

Cengizler Ç, Ün MK, Büyükkurt S. A Nature-Inspired Search Space Reduction Technique for Spine Identification on Ultrasound Samples of Spina Bifida Cases. Sci Rep. 2020 Jun 9;10(1):9280. doi: 10.1038/s41598-020-66468-x. PMID: 32518381; PMCID: PMC7283309. Disponível: https://pubmed.ncbi.nlm.nih.gov/32518381/

Wille DA, Padden B, Moehrlen U, Latal B, Schauer S, Kottke R, Grehten P, Meuli M. Impact of Brain Malformations on Neurodevelopmental Outcome in Children with a History of Prenatal Surgery for Open Spina Bifida. Fetal Diagn Ther. 2021;48(8):588-595. doi: 10.1159/000517972. Epub 2021 Aug 11. PMID: 34380134. Disponível: https://pubmed.ncbi.nlm.nih.gov/32518381/

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2023 Eliab Batista Barros, Maria Luiza Nóbrega Lins, Luciana Shiguemi Yamada, Patrick Romulo Correia da Silva, Ronald Santos da Silva, Isabela Maria Clemens Borges, Alexia Luana Roma Dos Santos, Laura Mansur Ferreira de Oliveira, Serena Kangombe Dipanda, Tiago Esteves do Rego, Tiago André Souza Melo Verçosa, Vitor Lins Acioli Barreto

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