Epidemiological Profile of Live Births with Congenital Heart Disease in Brazilian Regions.
PDF (Português (Brasil))

Keywords

Congenital heart disease, Live births, Regions, Brazil.

How to Cite

Barros, E. B., Yamada, L. S., Paiva, A. de O., Soares , A. E. R., Albuquerque, M. de A., Souza, G. C. de, Cavalcante, Y. C., Palumbo , R., Rego, T. E. do, & Rocha , G. B. de S. (2023). Epidemiological Profile of Live Births with Congenital Heart Disease in Brazilian Regions. Brazilian Journal of Implantology and Health Sciences, 5(5), 2316–2328. https://doi.org/10.36557/2674-8169.2023v5n5p2316-2328

Abstract

Aims: To conduct a descriptive epidemiological study of reported cases of live births with Congenital Heart Disease.

Methodology: This is a descriptive epidemiological study in which the epidemiological profile of reported cases of live births with congenital heart disease in Brazil will be analyzed based on data collected from the Information System on Live Births (SINASC) from 2012 to 2021, available at the Department of Informatics of the Unified Health System (DATASUS). In addition, a search was conducted on PUBMED and BVS using the keywords "Congenital heart disease, Live births, Regions, Brazil".

Results: From 2012 to 2021, in Brazil, there were 28,789,402 live births, with children with congenital heart disease accounting for 0.000875% (n = 25,212). The Southeast region recorded the highest number of cases, with 67.8% (n = 17,112), while the North region had the lowest prevalence, with 3.08% (n = 777). In terms of delivery methods, 71% were cesarean section (n = 17,902), 28.87% were vaginal deliveries (n = 7,281), and 0.11% were unidentified (n = 29). It's important to note that among live births, 10.6% (n = 3,057,372) were premature, while 27.44% (n = 6,920) of live births with congenital heart disease were premature. Regarding gender, males were more prevalent at 52.09% (n = 13,134), females accounted for 47.35% (n = 11,939), and 0.55% were unidentified (n = 139). The age of the mother at the time of delivery that stood out was between 30 and 34 years, with 23.65% (n = 5,964) of cases. The prevalent race/ethnicity among children with congenital heart disease was white, at 51.71% (n = 13,039).

Conclusion: There is a higher prevalence of live births with congenital heart diseases in the Southeast region, as well as a higher prevalence of males and individuals of white race/ethnicity. Prematurity was more common in children with congenital heart disease than in other live births, and the most prevalent age of mothers was between 30 and 34 years, with cesarean deliveries being predominant.

https://doi.org/10.36557/2674-8169.2023v5n5p2316-2328
PDF (Português (Brasil))

References

- Valentín R A. Cardiopatías congénitas en edad pediátrica, aspectos clínicos y epidemiológicos. Rev Med Electro 2018; 40(4): 1083-1099. Url: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-961282

- Saxena A. Doença cardíaca congênita na Índia: um relatório de status. Pediatra Indiano. 2018; 55: 1075–82. Url: https://pesquisa.bvsalud.org/portal/resource/pt/sea-79192;

- Baldacci S, Gorini F, Minichilli F, Pierini A, Santoro M, Bianchi F. Rassegna degli studi epidemiologici su fattori di rischio individuali e ambientali nell’eziologia dei difetti cardiaci congeniti. Epidemiol Prev. 2016; 40 (3-4): 185-196. Url: https://l1nq.com/UFgRj.

- Sun R, Liu M, Lu L, Zheng Y, Zhang P. Congenital heart disease: causes, diagnosis, symptoms, and treatments.Cell Bioch Bioph. 2015; 72: 857-860. Url: https://pubmed.ncbi.nlm.nih.gov/25638345/.

- Wolf M, Craig T. B. The molecular genetics of congenital heart disease: a review of recent developments. Cur Op Card. 2010; 25(3): 192. Url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930935/.

- Fahed Akl C, Gelb B D, Seidman J G, Seidman C F. Genetics of congenital heart disease: the glass half empty. Circ Res. 2013; 112(4): 707-720. Url: https://pubmed.ncbi.nlm.nih.gov/23410880/.

- Data and statistics on congenital heart defects. Centers for Disease Control and Prevention; 2022 [cited 2023 Jun 10]. Available from: https://www.cdc.gov/ncbddd/heartdefects/data.html

- Brasil, Ministério da Saúde. Banco de dados do Sistema Único de Saúde-DATASUS [citado 2023 Mai 20]. Disponível em http://www.datasus.gov.br

– Liu Y, Chen S, Zühlke L, Black GC, Choy MK, Li N, Keavney BD. Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies. Int J Epidemiol. 2019; 48(2):455-463. Url: https://pubmed.ncbi.nlm.nih.gov/30783674/.

- Van D L D, Konings E. E, Slager M. A, Witsenburg M, Helbing W. A, Takkenberg J. J, et al. Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis. J A Coll Card. 2011; 58(21): 2241-2247. Url: https://pubmed.ncbi.nlm.nih.gov/22078432/.

- Nembhard WN, Salemi JL, Ethen MK, Fixador DE, Dimaggio A, Canfield MA. Disparidades raciais/étnicas no risco de mortalidade na primeira infância entre crianças com defeitos cardíacos congênitos. Pediatri. 2011; 127(5).

- Bhat NK, Dhar M, Kumar R, Patel A, Rawat A, Kalra BP. Prevalence and pattern of congenital heart disease in Uttarakhand, India. Ind J Pediatri. 2013; 80: 281-285. Url: https://pubmed.ncbi.nlm.nih.gov/22492349/.

- Pace ND, Oster ME, Forestieri NE, Enright D, Knight J, Meyer RE. Sociodemographic Factors and Survival of Infants With Congenital Heart Defects. Pediatri. 2018; 42(3). Url: https://pubmed.ncbi.nlm.nih.gov/30111552/.

- Zloto K, Hochberg A, Tenenbaum-Gavish K, Berezowsky A, Barbash-Hazan S, Bardin R, et al. Fetal congenital heart disease-mode of delivery and obstetrical complications. BMC Preg Child. 2022; 22(1), 578. Url: https://pubmed.ncbi.nlm.nih.gov/35854228/

- Liu C, Lodge J, Flatley C, Gooi A, Ward C, Eagleson K, et al. Obstetric and perinatal outcomes in pregnancies with isolated foetal congenital heart abnormalities.J Maternal-Fetal Neo Med. 2019; 32(18): 2985-2992. Url: https://pubmed.ncbi.nlm.nih.gov/29544375/.

- Palma A, Morais S, Silva PV, Pires A. Congenital heart defects and preterm birth: Outcomes from a referral center. Rev Port Cardiol. 2023; 42(5): 403-410. Url: https://pubmed.ncbi.nlm.nih.gov/36828187/

- Liu S, Joseph KS, Lisonkova S, Rouleau J, Van den Hof M, Sauve R, et al. Association between maternal chronic conditions and congenital heart defects: a population-based cohort study. Can Peri Surv S. 2013; 128(6):583-9. Url: https://pubmed.ncbi.nlm.nih.gov/23812182/.

- Josefsson A, Kernell K, Nielsen NE, Bladh M, Sydsjö G. Reproductive patterns and pregnancy outcomes in women with congenital heart disease: a Swedish population-based study. Acta Obstet Gynecol Scand. 2011;90(6):659-65. Url: https://pubmed.ncbi.nlm.nih.gov/21314820/

- Wang Y, Liu G, Canfield MA. Rede Nacional de Prevenção de Defeitos Congênitos.Diferenças raciais/étnicas na sobrevivência de crianças dos Estados Unidos com defeitos congênitos: um estudo de base populacional. J Pediatr. 2015; 166(4):819–826.e1–e2

- Pei, L., Kang, Y., Zhao, Y., & Yan, H. Prevalence and risk factors of congenital heart defects among live births: a population-based cross-sectional survey in Shaanxi province, Northwestern China. BMC Pediatr. 2017; 17(1), 1-8.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2023 Eliab Batista Barros, Luciana Shiguem Yamada, André de Oliveira Paiva, Alícia Eduarda Rios Soares , Mateus de Araujo Albuquerque, Guilherme Carvalho de Souza, Yves Cardoso Cavalcante, Rafaella Palumbo , Tiago Esteves do Rego, Gabriela Barbosa de Sá Rocha