Abstract
COVID-19 is a relatively recent disease, with the first case reported at the end of 2019, and it spread rapidly, being declared a pandemic by the World Health Organization (WHO) in March 2020, which led to a significant strain on healthcare systems worldwide. Currently, with the development of various vaccines and vaccination campaigns, the situation is improving, with a decrease in the number of cases and deaths, and the disease appears to be increasingly under control. However, new reports of post-COVID-19 and post-vaccination complications emerge daily, leading to more research and studies, which are of utmost importance for a more efficient understanding of this virus and the development of more precise strategies to be taken. Therefore, the objective of this research was to analyze the relationship between cases of Deep Venous Thrombosis (DVT) from May 2020 to December 2021, following COVID-19 infection and/or COVID-19 vaccination. The study aimed to evaluate the frequency with which infection by the virus or vaccination against it preceded the episode of Thrombosis. In conclusion, this research found that despite the existence of cases that demonstrate that COVID-19 infection and/or vaccination preceded Thrombosis, it cannot be definitively stated that SARS-CoV-2 is the sole cause of Thromboembolism.
References
FAG. Trabalhos Acadêmicos: Manual para elaboração e apresentação. Cascavel: FAG, 2021.
Ochani RK, Asad A, Yasmin F, Shaikh S, Khalid H, Batra S, et al. COVID-19 pandemic: from origins to outcomes. A comprehensive review of viral pathogenesis, clinical manifestations, diagnostic evaluation, and management. Infez Med. 2021 Mar 1; 1:20-36.
International Society on Thrombosis and Haemostasis – ISTH [homepage na internet]. World Thrombosis Day: 13 October [acesso em 5 jun 2022]. Disponível em: https://www.worldthrombosisday.org/issue/vte/.
Cunha MJS, Pinto CAV, Guerra JCC, Tachibana A, Portugal MFC, Ferraz LJR, et al. Incidência, diagnóstico, métodos terapêuticos e desfechos de eventos tromboembólicos venosos em pacientes com COVID-19 em um hospital quaternário do Brasil. J Vas Bras. 2021 Jun 11; 20:e20200203.
Filho GB. Bogliolo Patologia. 8a ed. Rio de Janeiro: Guanabara Koogan; 2011.
Kumar V, Abbas AK, Aster JC. Robbins e Cotran Patologia: Bases Patológicas das Doenças. 9a ed. Rio de Janeiro: Elsevier; 2016.
Goswami J, MacArthur TA, Sridharan M, Pruthi RK, McBane RD, Witzig TE, et al. A Review of Pathophysiology, Clinical Features, and Management Options of COVID-19 Associated Coagulopathy. Shock. 2021 Jun 1; 55(6):700-716.
Vinayagam S, Sattu K. SARS-CoV-2 and coagulation disorders in different organs. Life Sci. 2020 Nov 1; 260:118431.
Hardy M, Lecompte T, Douxfils J, Lessire S, Dogné JM, Chatelain B, et al. Management of the thrombotic risk associated with COVID-19: guidance for the hemostasis laboratory. Thromb J. 2020 Sep 7; 18:17.
Orsi FA, De Paulo EV, Santos FO, Teruchkin MM, Campêlo DHC, Mello TT, et al. Guidance on diagnosis, prevention and treatment of thromboembolic complications in COVID-19: a position paper of the Brazilian Society of Thrombosis and Hemostasis and the Thrombosis and Hemostasis Committee of the Brazilian Association of Hematology, Hemotherapy and Cellular Therapy. Hematol Transfus Cell Ther. 2020; 42(4): 300-308.
Brandão SCS, Godoi ETAM, Ramos JOX, Melo LMMP, Sarinho ESC. COVID-19 grave: entenda o papel da imunidade, do endotélio e da coagulação na prática clínica. J Vasc Bras. 2020; 19:e20200131.
Mani A, Ojha V. Thromboembolism after COVID-19 Vaccination: A Systematic Review of Such Events in 286 Patients. Ann Vasc Surg. 22 May 11.
Dotan A, Shoenfeld Y. Perspectives on vaccine induced thrombotic thrombocytopenia. J Autoimmun. 2021 Jul; 121:102663.
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Copyright (c) 2023 Bruna Araújo Nicézio, Jeferson Freitas Toregeani, Gabrielle Nakayama Doreto, Michelle Policanti Morais , Julia Marega Galo, Yara Luiza Dondoni Celoni, Dayane Laís Rossi , Larissa Rossi, Danniely Alencar Sandim Melo