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Abstract
Introdução: A hidroxiapatita nanométrica (nHA) é um biomaterial bioativo amplamente estudado na odontologia regenerativa por sua semelhança com a matriz mineral do osso humano, promovendo osteocondução, biocompatibilidade e integração tecidual.
Objetivo: Avaliar, por meio de uma revisão sistemática, a eficácia da nHA em procedimentos cirúrgicos odontológicos, com foco em regeneração óssea, estabilidade de implantes e desempenho clínico.
Metodologia: A pesquisa foi conduzida nas bases PubMed, Scopus, Web of Science, EMBASE e BVS, incluindo estudos clínicos, in vivo, in vitro e revisões sistemáticas publicados entre 1999 e 2024. Os dados foram extraídos, organizados tematicamente e discutidos qualitativamente conforme as diretrizes PRISMA.
Resultados: Foram incluídos 22 estudos que demonstraram que a nHA apresenta desempenho superior na preservação alveolar, levantamento de seio maxilar e cobertura de implantes. Além disso, seu uso melhora a adesão celular, acelera a neoformação óssea e favorece a osseointegração, especialmente em protocolos de carga imediata.
Conclusão: A nHA é uma alternativa segura, eficaz e promissora para a regeneração óssea em cirurgia odontológica. No entanto, estudos clínicos de longo prazo ainda são necessários para padronizar suas aplicações e validar sua superioridade frente a outros biomateriais.
References
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Copyright (c) 2025 Ana Luísa Castro e Silva , Jennifer Vera Santos Gumert, Dyego Matielo Peres Lemos , Aléxia Caroline Leandro da Conceição , Rafael Avellar de Carvalho Nunes, Klarice Rafaella Menezes de Oliveira , Conrado Ribeiro de Oliveira, Cristiana Pereira Guedes, Henrique Galvão de Zúniga Honorato , Gabriel da Silva Costa, Rafael Arantes Soares Reis
