Keywords
Pandemia
Internações
How to Cite
Abstract
Introduction: Pulmonary embolism is a serious condition characterized by obstruction of pulmonary arteries, usually by blood clots. In women, the risk of developing this condition is increased. In this scenario, the increase in the use of electronic cigarettes in the country has become a concern, as its relationship with the development of the disease has been increasingly highlighted.Objective: To define the epidemiological profile of pulmonary embolism in women in Brazil in the context of increased use of electronic cigarettes. Methods: This is a retrospective horizontal epidemiological profile that uses data from Datassus, using the temporality parameters in relation to the use of electronic cigarettes in the years 2015 to 2024. Result: In 2022, Brazil recorded more than 18 thousand cases of pulmonary embolism in women, with an increase compared to 2017. In the same period, the use of electronic cigarettes among young people aged 15 to 24 grew 300% between 2015 and 2019, indicating a possible correlation. Discussion: Data analysis revealed a relationship between the increase in electronic cigarette use among young people and the increase in hospitalizations for pulmonary embolism in women. The age group that had the greatest relative increase over the analyzed period was 15 to 29 years old, highlighting the impact of electronic cigarettes on the incidence of the disease. Conclusion: The study highlights the relationship between the increase in pulmonary embolism and the use of electronic cigarettes, especially among young women aged 15 to 29, and seeks to encourage future public policies.
References
BARROS, V. et al. Análise epidemiológica do câncer de pulmão no Brasil em função do aumento do uso de cigarro eletrônico nos anos de 2017 a 2022. Brazilian Journal of Health Review, v. 8, n. 1, p. e77411–e77411, 7 fev. 2025.
BARKER, C. K.; PRINCY GHERA; HSU, B. The Evolution of a Pediatric Public Health Crisis: E-cigarette or Vaping-Associated Lung Injury. Pediatrics, 17 abr. 2024.
BHATTA, D. N.; GLANTZ, S. A. Association of E-Cigarette Use With Respiratory Disease Among Adults: A Longitudinal Analysis. American Journal of Preventive Medicine, v. 58, n. 2, dez. 2019.
BLADBJERG, E. M. Effects of different progestin regimens in hormone replacement therapy on blood coagulation factor VII and tissue factor pathway inhibitor. Human Reproduction, v. 17, n. 12, p. 3235–3241, 1 dez. 2002.
BORDERUD, S. P. et al. Electronic cigarette use among patients with cancer: Characteristics of electronic cigarette users and their smoking cessation outcomes. Cancer, v. 120, n. 22, p. 3527–3535, 22 set. 2014.
BROWN, C. J.; CHENG, J. M. Electronic cigarettes: product characterisation and design considerations. Tobacco Control, v. 23, n. suppl 2, p. ii4–ii10, 14 abr. 2014.
CAMENGA, D. R. et al. Appeal and Use of Customizable E-cigarette Product Features in Adolescents. Tobacco Regulatory Science, v. 4, n. 2, p. 51–60, 1 mar. 2018.
CHAITANYA THANDRA, K. et al. Epidemiology of lung cancer. Współczesna Onkologia, v. 25, n. 1, p. 45–52, 23 fev. 2021.
DAWKINS, L. et al. The electronic-cigarette: effects on desire to smoke, withdrawal symptoms and cognition. Addictive Behaviors, v. 37, n. 8, p. 970–973, 1 ago. 2012.
Dispositivos Eletrônicos para Fumar (DEF). Disponível em: <https://www.gov.br/inca/pt-br/assuntos/gestor-e-profissional-de-saude/observatorio-da-politica-nacional-de-controle-do-tabaco/dados-e-numeros-do-tabagismo/def-dados-e-numeros>.
DUTRA, L. M.; GLANTZ, S. A. Electronic Cigarettes and Conventional Cigarette Use Among US Adolescents. JAMA Pediatric, v. 168, n. 7, p. 610, 1 jul. 2014.
EAST, K. et al. Exposure to negative news stories about vaping, and harm perceptions of vaping, among youth in England, Canada, and the US before and after the outbreak of E-cigarette or Vaping-Associated Lung Injury (EVALI). Nicotine & Tobacco Research, v. 24, n. 9, 3 abr. 2022.
ELLINGTON, S. et al. Update: Product, Substance-Use, and Demographic Characteristics of Hospitalized Patients in a Nationwide Outbreak of E-cigarette, or Vaping, Product Use–Associated Lung Injury — United States, August 2019–January 2020. MMWR. Morbidity and Mortality Weekly Report, v. 69, n. 2, p. 44–49, 17 jan. 2020.
FARLEY, T. M. et al. Combined oral contraceptives, smoking, and cardiovascular risk. Journal of Epidemiology & Community Health, v. 52, n. 12, p. 775–785, 1 dez. 1998.
GOLDHABER, S. Z.; BOUNAMEAUX, H. Embolia pulmonar e trombose venosa profunda. Lancet, 2012;379:1835–1846. doi: 10.1016/S0140-6736(11)61904-1.
GOTTS, J. E. et al. What are the respiratory effects of e-cigarettes? BMJ, v. 366, n. 5275, p. l5275, 30 set. 2019.
GRANA, R.; BENOWITZ, N.; GLANTZ, S. A. E-Cigarettes: A Scientific Review. Circulation, v. 129, n. 19, p. 1972–1986, 13 maio 2014.
HAN, E. L. et al. Concerns Over Vuse E-cigarette Digital Marketing: Implications for Public Health Regulation (Preprint). JMIR Formative Research, 17 nov. 2023.
Hospitalizations and Deaths Associated with EVALI. Disponível em: <https://www.sopterj.com.br/hospitalizations-and-deaths-associated-with-evali/>.
KAISAR, M. A. et al. Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure? Redox Biology, v. 13, p. 353–362, out. 2017.
KRESLAKE, J. M. et al. Youth and young adult risk perceptions and behaviours in response to an outbreak of e-cigarette/vaping-associated lung injury (EVALI) in the USA. Tobacco Control, v. 31, n. 1, p. tobaccocontrol-2020-056090, 13 jan. 2021.
LEE, J. G. L.; GRIFFIN, G. K.; MELVIN, C. L. Tobacco use among sexual minorities in the USA, 1987 to May 2007: a systematic review. Tobacco Control, v. 18, n. 4, p. 275–282, 10 fev. 2009.
MARTIN, K. A. et al. Tendências temporais nas taxas de mortalidade por embolia pulmonar nos Estados Unidos, 1999 a 2018. J. Am. Heart Assoc., 2020;9:e016784. doi: 10.1161/JAHA.120.016784.
NAIK, P. et al. Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood-brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe? BMC Neuroscience, v. 15, n. 1, p. 51, 2014.
OLANIYI FADEYI et al. Thromboembolism Triggered by a Combination of Electronic Cigarettes and Oral Contraceptives: A Case Report and Review of Literature. Journal of Investigative Medicine High Impact Case Reports, v. 11, 1 jan. 2023.
SASSANO, M. F. et al. Evaluation of e-liquid toxicity using an open-source high-throughput screening assay. PLOS Biology, v. 16, n. 3, p. e2003904, 27 mar. 2018.
SCHIER, J. G. et al. Severe Pulmonary Disease Associated with Electronic-Cigarette–Product Use — Interim Guidance. MMWR. Morbidity and Mortality Weekly Report, v. 68, n. 36, p. 787–790, 13 set. 2019.
STRATTON, K.; KWAN, L. Y.; EATON, D. L. (EDS.). Public Health Consequences of E-Cigarettes. Washington, D.C.: National Academies Press, 2018.
TEMPLE, J. R. et al. E-cigarette Use of Young Adults: Motivations and Associations with Combustible Cigarette, Alcohol, Marijuana, and Other Illicit Drugs. The American Journal on Addictions, v. 26, n. 4, p. 343–348, 1 jun. 2017.
ZHENG, X. et al. Social media and E-cigarette use among US youth. Addictive Behaviors, v. 119, p. 106916, ago. 2021.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2025 Lucas Rocha Santana da Silva, Luciano de Castro Rezende Araújo Teixeira, Katia Talita dos Santos Barros, Lucas Ferreira Melo, Pedro Victor Rocha Trevilato, Thiago Erick Moreira Rocha, Patrícia Lira Silva, Luiza Rocha Santana da Silva