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Abstract
Buschke-Löwenstein tumor (TBL) is a rare and aggressive form of condyloma acuminata that may be associated with Human Papillomavirus (HPV) types 6 and 11. This case report describes the clinical management of a 54-year-old patient with a history of type 2 diabetes mellitus, leprosy and a history of HPV infection, who developed TBL in the vulvar region. After initial treatment with cauterization and surgical resection was unsuccessful, the decision was made to use Imiquimod, an immunomodulator that demonstrated significant efficacy, resulting in the regression of the lesions. This case emphasizes the importance of multimodal treatment, taking into account the patient's comorbidities and the invasive nature of TBL.
References
SANTOS, E.; SOUZA, R. Tratamento do tumor de Buschke-Löwenstein: uma revisão de literatura. Revista Brasileira de Dermatologia, v. 93, n. 4, p. 123-130, 2018.
OLIVEIRA, M.; SILVA, J. Imiquimod no tratamento do HPV: revisão de casos clínicos. Journal of Dermatology Research, v. 45, n. 2, p. 98-104, 2019.
MENDONÇA, L.; COSTA, A. Hanseníase e HPV: implicações no diagnóstico e tratamento. Revista de Medicina Imunológica, v. 12, n. 1, p. 45-50, 2020.
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