Abordagem integrada no tratamento do transtorno bipolar

Authors

  • Daniella Rodrigues de Carvalho INAPÓS
  • Elen Miranda de Oliveira Unifacs
  • Geisa Cerqueira de Brito Unifacs
  • Fernanda Cristina Cardozo Ribeiro ESCS
  • Gabriela Aime Hassler Sugai ESCS
  • Katia Cristina Pinheiro Godinho Carabolante UniBH
  • Sophye Bianco de Soto Inoue UniSALESIANO
  • Tatiane Cordeiro Breda de Siqueira FAPI
  • Livia Ferrari Gilioli UNIFAE
  • Rafaella Rocha Kolinski Universidade Franciscana
  • Catcherine Tombini Brum UPF
  • Valentina de Sá Nogueira Leite UVA

DOI:

https://doi.org/10.36557/2674-8169.2025v7n1p2048-2058

Keywords:

Transtorno bipolar, Adesão e cooperação ao tratamento, Psicoterapia

Abstract

This article aims to conduct a scientific literature review on the integrated approach to the treatment of bipolar disorder, emphasizing combined therapeutic methods, clinical efficacy, and impact on patients' quality of life. For this purpose, the search engines PubMed, Scopus, and Web of Science were used, with the keywords "Bipolar disorder, Integrated treatment, Psychotherapy, Mood stabilizers." The review revealed that bipolar disorder, due to its complexity, requires multimodal interventions that combine the use of mood stabilizers, psychotherapy, lifestyle changes, and psychoeducational support. Integrated strategies proved effective in improving treatment adherence, reducing relapses, and stabilizing mood in the long term. The combination of medications, such as lithium and anticonvulsants, with psychological therapies, such as cognitive-behavioral therapy and family-focused therapy, showed superior results compared to isolated approaches. Furthermore, promoting healthy habits, such as sleep regulation and physical exercise, proved essential in managing symptoms and improving patients' quality of life.

This article aims to conduct a scientific literature review on the integrated approach to the treatment of bipolar disorder, emphasizing combined therapeutic methods, clinical efficacy, and impact on patients' quality of life. For this purpose, the search engines PubMed, Scopus, and Web of Science were used, with the keywords "Bipolar disorder, Integrated treatment, Psychotherapy, Mood stabilizers." The review revealed that bipolar disorder, due to its complexity, requires multimodal interventions that combine the use of mood stabilizers, psychotherapy, lifestyle changes, and psychoeducational support. Integrated strategies proved effective in improving treatment adherence, reducing relapses, and stabilizing mood in the long term. The combination of medications, such as lithium and anticonvulsants, with psychological therapies, such as cognitive-behavioral therapy and family-focused therapy, showed superior results compared to isolated approaches. Furthermore, promoting healthy habits, such as sleep regulation and physical exercise, proved essential in managing symptoms and improving patients' quality of life.

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References

COLOM, F. et al. A randomized trial on the efficacy of group psychoeducation in the prophylaxis of recurrences in bipolar patients whose disease is in remission. Archives of General Psychiatry, v. 60, n. 4, p. 402-407, 2003. DOI: https://doi.org/10.1001/archpsyc.60.4.402.

GEDDES, J. R.; MIKLOWITZ, D. J. Treatment of bipolar disorder. The Lancet, v. 381, n. 9878, p. 1672-1682, 2013. DOI: https://doi.org/10.1016/S0140-6736(13)60857-0.

GITLIN, M. J.; SWANN, A. C.; GHAEMI, S. N. Lithium and Lamotrigine in the management of bipolar disorder. Journal of Clinical Psychiatry, v. 65, n. 6, p. 850-856, 2004. DOI: 10.4088/JCP.v65n0615.

GRANDE, I. et al. Bipolar disorder. The Lancet, v. 387, n. 10027, p. 1561-1572, 2016. DOI: https://doi.org/10.1016/S0140-6736(15)00241-X.

MIKLOWITZ, D. J. et al. Family-focused treatment for bipolar disorder. Journal of Clinical Psychiatry, v. 68, n. 6, p. 984-991, 2007. DOI: 10.4088/JCP.v68n0615.

NIVOLI, A. M. et al. Pharmacological treatments for bipolar disorder: A systematic review. Bipolar Disorders, v. 13, n. 3, p. 250-263, 2011. DOI: 10.1111/j.1399-5618.2011.00888.x.

SYLVIA, L. G. et al. Association of exercise with quality of life and mood symptoms in a comparative effectiveness study of bipolar disorder. Journal of Affective Disorders, v. 151, n. 2, p. 722-727, 2013. DOI: https://doi.org/10.1016/j.jad.2013.06.002.

VIEIRA, E.; TOHEN, M.; BOWDEN, C. L. Long-term outcomes in bipolar disorder: A review of evidence from pharmacotherapy studies. Psychiatry Research, v. 266, p. 182-190, 2018. DOI: 10.1016/j.psychres.2018.04.046.

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Published

2025-01-27

How to Cite

Rodrigues de Carvalho, D., Oliveira, E. M. de, Brito, G. C. de, Ribeiro, F. C. C., Sugai, G. A. H., Carabolante, K. C. P. G., Inoue, S. B. de S., Siqueira, T. C. B. de, Gilioli, L. F., Kolinski, R. R., Brum, C. T., & Leite, V. de S. N. (2025). Abordagem integrada no tratamento do transtorno bipolar. Brazilian Journal of Implantology and Health Sciences, 7(1), 2048–2058. https://doi.org/10.36557/2674-8169.2025v7n1p2048-2058

Issue

Vol. 7 No. 1 (2025): BJIHS QUALIS B3 - FATOR DE IMPACTO SJIF 5.807 - ÍNDICE H 22

Section

Literature Review

License

Copyright (c) 2025 Daniella Rodrigues de Carvalho, Elen Miranda de Oliveira, Geisa Cerqueira de Brito, Fernanda Cristina Cardozo Ribeiro, Gabriela Aime Hassler Sugai, Katia Cristina Pinheiro Godinho Carabolante, Sophye Bianco de Soto Inoue, Tatiane Cordeiro Breda de Siqueira, Livia Ferrari Gilioli, Rafaella Rocha Kolinski, Catcherine Tombini Brum, Valentina de Sá Nogueira Leite

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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