Analysis of current treatments indicated for irritable bowel syndrome: an integrative literature review
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Keywords

Keywords: Irritable Bowel Syndrome; Management; Probiotics; FODMAP; Treatment.

How to Cite

Albuquerque Miranda, A. L., Silva, I. F., Murad, M. M., Cavalcante, L. S., Tartaglia, T. T. de S. L., Ramos, F. R. de O., Fialho, S. M. M., Mucci, A. B., dos Santos, R. B., Nunes, G. B. M. C., Pereira, A. L. E. de B. E., de Morais, D. V., & de Sousa, C. A. (2025). Analysis of current treatments indicated for irritable bowel syndrome: an integrative literature review. Brazilian Journal of Implantology and Health Sciences, 7(1), 1748–1767. https://doi.org/10.36557/2674-8169.2025v7n1p1748-1767

Abstract

Introduction: Irritable Bowel Syndrome (IBS) is a chronic functional gastrointestinal condition that affects 10% to 20% of the world population, predominantly young or middle-aged women. It is characterized by symptoms such as abdominal pain, distension, diarrhea or constipation, often aggravated by emotional and dietary factors. Although there is no definitive cure, several therapeutic approaches have been proposed. Methodology: This study carried out an integrative review of the literature in databases such as PubMed, LILACS and Scielo, using the descriptors “Irritable bowel syndrome” and “treatment”. Articles between 2019 and 2024, in English and Portuguese, were considered, strictly following inclusion and exclusion criteria. Results and Discussion: Sixteen studies were evaluated, which assessed the following therapeutic options: LOW FODMAP diet, probiotics, fecal microbiota transplant, amitriptyline, geraniol, plecanatide, rifaximin, vibegron, physical activity and neuromodulators. The combination of dietary, pharmacological and behavioral interventions is essential for the management of IBS. Despite the efficacy of diets and probiotics, long-term adherence may be limited. Pharmacological approaches offer a solution in specific cases, and it is necessary to assess the clinical picture on an individual basis. Conclusion: Although there is no cure, the therapeutic approaches reviewed in this study demonstrate great potential in the management of symptoms.

https://doi.org/10.36557/2674-8169.2025v7n1p1748-1767
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Copyright (c) 2025 Ana Luisa Albuquerque Miranda, Isabella Ferreira Silva, Marina Messias Murad, Leticia Silva Cavalcante, Tamara Trevenzoli de Souza Lima Tartaglia, Fábio Ruela de Oliveira Ramos, Sarah Maria Mol Fialho, Aliny Barbosa Mucci, Ranielle Bruno dos Santos, Gustavo Batista Mendes Costa Nunes, Ana Luísa Esteves de Barcellos Emery Pereira, Diogo Vieira de Morais, Christiane Alves de Sousa

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