Abstract
This article aims to conduct a literature survey and analyze the importance and efficacy of the therapeutic use of Cannabidiol (CBD) in the treatment of epilepsy, as well as explore its benefits. This is an integrative review research, and the following indexes were used for the searches: Virtual Health Library (BVS), Latin American and Caribbean Database of Health Sciences Information (LILACS), National Library of Medicine (PUBMED) and the Online Medical Literature Search and Analysis System (MedLine) through the terms contained in the structured vocabulary of Health Sciences Descriptors (DeCS). Severe epilepsies are characterized by frequent seizures and in the vast majority of cases conventional treatment does not have the desired effect, causing a major impact on the quality of life of those living with this condition. Thus, studies show that an effective alternative would be CBD-based treatment, which acts by significantly reducing the frequency of epileptic seizures, especially epilepsies resistant to conventional treatment, Lennox-Gastaut Syndrome, Dravet Syndrome, Doose Syndrome, Idiopathic Epilepsy and Refractory Developmental Epileptic Encephalopathies among children, adolescents and adults. It is concluded that although the use of cannabis, especially cannabidiol (CBD), has proven to be effective and safe in the treatment of epilepsy, acting to reduce the frequency of epileptic seizures, there are still limitations in current knowledge and regulatory issues that restrict its specific and expanded use.
Keywords: Cannabidiol; Epilepsy; and Drug-Resistant Epilepsy.
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Copyright (c) 2025 JOENA GABRIELA SILVA MORAIS, TÂMIA RAYARA CARVALHO ARAÚJO DA SILVA, POLLYANNA NASCIMENTO DA SILVA, DANILO PEREIRA PINHEIRO, ESTHER LOBATO BRITO, EMILLY LUISE MOURA DE SOUSA, BLENDA SILVA DOS SANTOS, EMANUELY PEREIRA ANTERO, LUANA REIS CARNEIRO, JOSÉ RICARDO PATRÍCIO DA SILVA SOUZA