Abstract
The journey to recovery from substance addiction requires a carefully tailored approach, where pharmacological interventions, combined with behavioral therapies and social support, are the pillars for building a sustained and meaningful recovery. The purpose of this research was to study pharmacological interventions currently available for the treatment of substance dependence. With this goal in mind, a systematic literature review was conducted, selecting scientific research published between 2019 and 2024, found in the Scopus, Semantic Scholar, Scielo, Medline and Lilacs databases. After examining the results, the main conclusion of this study is the importance of restoring neurochemical balance as a fundamental approach in the treatment of substance addiction. Although pharmacological interventions offer significant benefits, it is essential to address challenges such as side effects and long-term adherence in order to improve their effectiveness. It also highlights the continued need for research to better understand the comparative effectiveness of different pharmacological interventions and to develop more comprehensive strategies to address the challenges associated with treating addiction.
References
Ferreira LM, Rêgo HMA, Souza AA, Marques LM, Bastos MTB, Koch TB, Matheus GD. Abuso de Substâncias e Emergências Psiquiátricas: Avaliação Integrada e Intervenções Eficazes. Brazilian Journal of Implantology and Health Sciences, 2023;5(5):5795-5813. https://bjihs.emnuvens.com.br/bjihs/article/view/1109
Leal R. Uso indevido e dependência de opioides: da prevenção ao tratamento. Revista de Medicina de família e Saúde mental, 2020;2(1). https://revista.unifeso.edu.br/index.php/medicinafamiliasaudemental/article/view/2239
Silva FC, Ricardi ER. Uso terapêutico de antidepressivos no abuso de substâncias psicoativas. Revista Científica Unilago, 2021;1(1). https://revistas.unilago.edu.br/index.php/revista-cientifica/article/view/593
Pereira LFG, Ricardo IM, Aquino RL, Xavier DAA. Internação compulsória de dependentes químicos: violação do direito de liberdade ou proteção do direito à vida?. Hygeia: Revista Brasileira de Geografia Médica e da Saúde, 2020;16(11). https://seer.ufu.br/index.php/hygeia/article/download/47423/28909
Souza AP, Oliveira BM, Silva EFL, Rocha, GS, Almeida ACG, Brito MAM. Atenção farmacêutica no uso indevido de medicamentos para emagrecimento: revisão sistemática. Research, Society and Development, 2023;12(6):e10712642133-e10712642133. https://rsdjournal.org/index.php/rsd/article/view/42133.
Silva RM, Teixeira, DA, Kokudai RLN. O uso de fármacos no tratamento do alcoolismo. Revista Multidisciplinar do Nordeste Mineiro, 2022;8(1). http://revista.unipacto.com.br/index.php/multidisciplinar/article/view/1127.
Santos SMP, Andrade LG. Fármacos para o tratamento do alcoolismo. Revista Ibero-Americana de Humanidades, Ciências e Educação, 2022;8(3):558-567. https://periodicorease.pro.br/rease/article/view/4614.
Squeglia LM, Fadus MC, McClure EA, Tomko RL, Gray KM. Pharmacological treatment of youth substance use disorders. Journal of child and adolescent psychopharmacology, 2019;29(7):559-572. https://www.liebertpub.com/doi/abs/10.1089/cap.2019.0009.
Chamberlain SR, Grant JE. Efficacy of pharmacological interventions in targeting decision-making impairments across substance and behavioral addictions. Neuropsychology review, 2019;29(1):93-102. https://link.springer.com/article/10.1007/s11065-019-09400-z.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2024 Matheus Lobato Farinon , Sara Izabel Cargnin Henrique Neves , Luiz Carlos Illafont Coronel