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Abstract
This article reviews the physiological foundations, evidence-based best practices, and technological advances applied to wound healing. Research was conducted using renowned scientific platforms, including PubMed, Scopus, Web of Science, and UpToDate, along with classic textbooks in plastic surgery, such as Grabb and Smith's Plastic Surgery and Plastic Surgery: Principles and Practice. The review covers systemic and local factors influencing tissue repair, highlighting approaches like debridement, maintaining a moist environment, and nutritional supplementation. Innovative therapies such as negative pressure wound therapy, tissue bioengineering, and cellular therapies are also explored. We conclude that an integrated and personalized evidence-based approach is essential to optimize clinical outcomes and reduce complications in complex wounds.
References
Referências
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