Keywords
Infecções por Rhabdoviridae
Vacina Antirrábica
How to Cite
Abstract
Human rabies, a viral zoonosis caused by Rabies virus (RABV), of the genus Lyssavirus and family Rhabdoviridae, represents a serious public health challenge, especially in developing countries. The disease is almost always fatal after the onset of symptoms, despite advances in prophylaxis and treatment. This study reviews the epidemiology, transmission, prophylaxis, and new therapies for rabies, with the aim of updating the available information and exploring new therapeutic and public health approaches. The research, carried out in June 2024, was conducted through the BVS, PubMed, SciELO, Google Scholar, and UpToDate databases, covering studies published between 2020 and 2024 in Portuguese, Spanish, and English. Descriptors such as "Rabies", "Rhabdoviridae Infections", and "Rabies Vaccine" were used, resulting in 1882 initial studies. After rigorous screening, 300 articles were considered eligible and 16 were analyzed in detail. The analysis highlighted the importance of mass vaccination, early diagnosis and prophylaxis strategies in preventing the disease. Despite the challenges, strengthening surveillance programs and public education are crucial for rabies control, with advances in vaccines and therapies offering a positive outlook for the future.
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Copyright (c) 2024 Pedro Fechine Honorato, Dhiego Alves de Lacerda, Celine Souza de Menezes Sá, Eryclys Abreu de Lira, Francisca Evelyn Abreu de Lira, Renata Braga Vale, Ubiraídys de Andrade Isidorio