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Abstract
This article aims to scan the current medical literature on the relationship between rhabdomyolysis and its renal complications, including mechanisms, diagnosis and treatment. This is an integrative review using the Virtual Health Library (VHL), LILACS and PubMed as a database over the last 10 years. It is concluded that the main complication of rhabdomyolysis is acute kidney injury (RAI), since the muscle components released into the bloodstream are nephrotoxic and treatment based on the conjugation of deferoxamine to adamantyl derivatives represents a promising approach to overcome the challenges associated with its intrinsic toxicity.
Keywords: Rhabdomyolysis, Renal Insufficiency, Therapeutics.
References
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Copyright (c) 2024 Davi Leoni, Laysa Moreira Peterle, Maria Eduarda Zanette Macedo , Ana Karolline Rocha de Castro , Wedja Kauany Rodrigues Santos , Pietra Cristina Gomes Pessini , Lívia Busatto Pena, Angélica Pimenta do Amaral, Alice Sales Zampirolli , Laísa Marchette Ciciliotti, Natalia Bianchini Pinto