Clinical treatment of peri-implantitis with maintenance of granulation tissue
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Keywords

Granulation Fabric
Implant dentistry
Peri-implantitis

How to Cite

Clares, M. D., & Scilio , S. G. . (2019). Clinical treatment of peri-implantitis with maintenance of granulation tissue. Brazilian Journal of Implantology and Health Sciences, 1(7), 192–206. https://doi.org/10.36557/2674-8169.2019v1n7p192-206

Abstract

Objectives: The aim of this study was to evaluate a non-surgical approach to peri-implantitis through mechanical debridement and local detoxification, leaving granulation tissue in the peri-implant wells.

Materials and Methods: An analysis of the results of two non-surgical protocols was performed: mechanical debridement plus chemical detoxification with 0.2% chlorhexidine and chlortetracycline hydrochloride (test) and mechanical debridement alone (control). Measurements were collected at baseline, 3, 24, and 36 months after treatment.

Results: Seventy-five implants with peri-implantitis were included. At a 36-month evaluation, the mean probing depth was 3.15 ± 0.32 mm for the test group and 5.97 ± 0.90 mm for the control group, with a significant difference. An improvement in marginal bone level was recorded for the test group, regardless of whether the control group showed additional marginal bone loss. Treatment success was 100% in the test group and 31.4% in the control group.

Conclusion: Non-surgical implant debridement by itself did not seem efficient in the treatment of peri-implantitis. Additional longitudinal studies are needed to evaluate the effectiveness of mechanical debridement with chemical detoxification and removal of granulation tissues against mechanical debridement with chemical detoxification only.

https://doi.org/10.36557/2674-8169.2019v1n7p192-206
PDF (Português (Brasil))

References

1- Mombelli A, Lang NP. The diagnosis and treatment of peri-implantitis. Periodontol 2000. 1998;17:63–76.

2- Derks J, Tomasi C. Peri-implant health and disease. A systematic review of current epidemiology. J Clin Periodontol. 2015;16:158–171.

3- Albrektsson T, Canullo L, Cochran D, et al. “Peri‐implantitis”: A complication of a foreign body or a man‐made “disease.” Facts and fiction. Clin Implant Dent Relat Res. 2016;18:840–849.

4- Alysson Henrique Neves Ramos e Eber Coelho Paraguassu. Adult health-related quality of life and associated factors: a population-based study. Periódicos Brasil.Odontologia. v.1, n.3, p. 42-55, 2019.

5- Karring ES, Stavropoulos A, Ellegaard B, et al. Treatment of peri‐implantitis by the Vector® system. Clin Oral Implants Res. 2005;16:288–293.

6- Sanz M, Alandez J, Lazaro P, et al. Histo-pathologic characteristics of peri-implant soft tissues in Branemark implants with 2 distinct clinical and radiological patterns. Clin Oral Implants Res. 1990;2:128–134.

7- Heydenrijk K, Meijer JA, Van der Reijden WA, et al. Microbiota around root-form endosseous implants: A review of the literature. Int J Oral Maxillofac Implants. 2002;17:829–838.

8- Papathanasiou E, Finkelman M, Hanley J, et al. Prevalence, etiology and treatment of peri-implant mucositis and peri-implantitis: A survey of periodontists in the United States. J Periodontol. 2016;87:493–501.

9- Lindhe J, Nyman S. Scaling and granulation tissue removal in periodontal therapy. J Clin Periodontol. 1985;12:374–388.

10- Steiner GG, Francis W, Burrell R, et al. The healing socket and socket regeneration. Compend Contin Educ Dent. 2008;29:114–124.

11- Lucas Cesar Calistro e Eber Coelho Paraguassu. Reflejo cardíaco trigémino tardío después de la cirugía buccomaxilofacial: reporte de caso. Periódicos Brasil.Odontologia. v.1, n.3, p. 56-61, 2019.

12- Ronay V, Belibasakis GN, Schmidlin PR, et al. Infected periodontal granulation tissue contains cells expressing embryonic stem cell markers. A pilot study Schweiz. Monatsschr Zahnmed. 2013;123:12–16.

13- Crespi R, Capparè P, Gastaldi G, et al. Reactive soft tissue preservation in large bone defects after tooth extractions. A cone beam study. Int J Oral Maxillofac Implants. 2016;31:179–185.

14- Crespi R, Capparè P, Gastaldi G, et al. Reactive soft tissue preservation in maxillary large bone defects. Int J Oral Maxillofac Implants. 2016;31:179–185.

15- Salvi GE, Lang NP. Diagnostic parameters for monitoring peri-implant conditions. Int J Oral Maxillofac Implants. 2004;19:116–127.

16- Charalampakis G, Rabe P, Leonhardt A, et al. A follow-up study of periimplantitis cases after treatment. J Clin Periodontol. 2011;23:1045–1054.

17- Esposito M, Grusovin MG, Worthington HV. Treatment of periimplantitis: What interventions are effective? A Cochrane systematic review. Eur J Oral Implantol. 2012;5:s21–s41.

18- Renvert S, Lessem J, Dahlen G, et al. Mechanical and repeated antimicrobial therapy using a local drug delivery system in the treatment of peri-implantitis: A randomized clinical trial. J Periodontol. 2008;79:836–844.

19- João Marcelo Campos. The use of medical and phytotherapic plants in brazilian public health. Periódicos Brasil.Medicina e Ciências da Saúde. v.1, n.1, p. 01-10, 2019

20- Claffey N, Clarke E, Polyzois I, et al. Surgical treatment of peri‐implantitis. J Clin Periodontol. 2008;35:316–332.

21- Schwarz F, Sahm N, Iglhaut G, et al. Impact of the method of surface debridement and decontamination on the clinical outcome following combined surgical therapy of peri-implantitis: A randomized controlled clinical study. J Clin Periodontol. 2011;38:276–284.

22- Serino G, Turri A. Outcome of surgical treatment of peri-implantitis: Results from a 2-year prospective clinical study in humans. Clin Oral Implants Res. 2011;22:1214–1220.

23- Meier RM, Pfammatter C, Zitzmann NU, et al. Surface quality after implantoplasty. Swiss Dent J. 2011;122:714–724.

24- Heitz-Mayfield LJA, Mombelli A. The therapy of peri-implantitis: A systematic review. Int J Oral Maxillofac Implants. 2014;29:325–345.

25- Mombelli A, Feloutzis A, Bragger U, et al. Treatment of periimplantitis by local delivery of tetracycline. Clinical, microbiological, and radiological results. Clin Oral Implants Res. 2001;12:287–294.

26- Jamille dos Passos Lacerda. Qual a idade da terapia com implantes em termos de perdas precoces de implantes?. Periódicos Brasil.Pesquisa Científica. v.1, n.4, p. 31-46, 2019.

27- Heasman PA, Heasman F, Stacey F, et al. Local delivery of (CHX) (CHX) gluconate (Periochip) in periodontal maintenance patients. J Clin Periodontol. 2001;28:90–95.

28- Azmak N, Atilla G, Luoto H, et al. The effect of subgingival controlled-release delivery of (CHX) (CHX) chip on clinical parameters and matrix metalloproteinase-8 levels in gingival crevicular fluid. J Periodontol. 2002;73:608–615.

29- Häkkinen L, Larjava H. Characterization of fibroblast clones from periodontal granulation tissue in vitro. J Dent Res. 1992;71:1901–1907.

30- Hung TY, Lin HC, Chan YJ, et al. Isolating stromal stem cells from periodontal granulation tissues. Clin Oral Invest. 2012;16:1171–1180.

31- Ben-Shushan E, Thompson JR, Gudas LJ, et al. Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site. Mol Cell Biol. 1998;18:1866–1878.

32- Boiani M, Kehler J, Scholer HR. Activity of the germline-specific Oct4-GFP transgene in normal and clone mouse embryos. Methods Mol Biol. 2004;254:1–34.

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