Deep Brain Stimulation Therapy for Disorders Treatment-Resistant Psychiatric Disorders

Abstract

Introduction: Deep Brain Stimulation (DBS) Therapy is a neuromodulatory intervention that has shown significant potential in treating psychiatric disorders resistant to conventional treatments. Objectives: To evaluate symptom reduction in patients with resistant psychiatric disorders. Methodology: They consisted of a systematic literature review, where relevant articles were searched in academic databases. The inclusion criteria were defined to select studies that evaluated the surgical treatment of nephrotic syndrome and its strategies to control proteinuria and preserve renal function. For data collection, the following databases were used: Scientific Electronic Library Online (SCIELO), PubMed and Latin American Caribbean Literature in Health Sciences (LILACS). Various types of publications, such as scientific articles, monographs and magazines, were consulted to obtain relevant information on the topic. Results and Discussions: Results of Deep Brain Stimulation (DBS) Therapy for treatment-resistant psychiatric disorders have demonstrated a significant reduction in symptoms in a substantial proportion of patients. Clinical improvement was observed in both major depression and obsessive-compulsive disorder, indicating the therapeutic potential of DBS in these conditions. Furthermore, adverse effects were generally tolerable, highlighting the relative safety of this procedure. These findings suggest that DBS may be a valuable option for patients who do not respond to conventional treatments, although more research is needed to fully understand its mechanisms of action and optimize its clinical application. Conclusion: Deep Brain Stimulation (DBS) Therapy shows a promising approach for treating resistant psychiatric disorders such as major depression and obsessive-compulsive disorder. The results indicate a significant reduction in symptoms in many patients, highlighting DBS as a viable alternative when conventional treatments fail. However, long-term efficacy and safety require further research. DBS represents a significant advancement in Interventional Psychiatry, offering hope for patients with severe and refractory conditions.