Endometrial Control and Efficacy of Intrauterine Devices: A Review of the Advantages and Limitations of LNG-IUD
PDF (Português (Brasil))

Keywords

Intrauterine Devices; Endometrial Control; Menstrual Bleeding.

How to Cite

Valena Paiva da Fonseca, J., Torres Begot da Rocha, C. K., Fonsceca, G., Bressan Pizarro, M., Lugli, L., Topassi, C., Brum Paes, M. L., Moura Rocha, I., Clarkes Pereira Gonçalves, B., Heiko Filgueira Otino, J., Doretto Oliveira , L., & Sari Junior, C. F. (2024). Endometrial Control and Efficacy of Intrauterine Devices: A Review of the Advantages and Limitations of LNG-IUD. Brazilian Journal of Implantology and Health Sciences, 6(6), 2143–2153. https://doi.org/10.36557/2674-8169.2024v6n6p2143-2153

Abstract

This study evaluated the effectiveness of intrauterine devices (IUDs) in endometrial control, exploring the underlying mechanisms behind clinical benefits and investigating the advantages and limitations of different types of IUDs. The integrative review was meticulously planned to ensure a comprehensive assessment of the effects of IUDs on endometrial control, focusing on cellular alterations and endometrial conditions. The reviewed studies highlight the efficacy of the LNG-IUD in reducing menstrual volume, resulting in higher continuation rates for contraceptive purposes. However, challenges such as irregular bleeding require additional interventions. Intensive counseling is crucial for personalized strategies that meet individual patient needs. Anatomical factors, such as uterine cavity size, influence clinical outcomes, especially for LNG-IUD users. Additionally, the clinical profile of patients plays an important role in managing the LNG-IUD, particularly in treating abnormal uterine bleeding. The conclusions emphasize the complexity of using IUDs and the need for a comprehensive and personalized approach to optimize their effectiveness and clinical acceptance.

https://doi.org/10.36557/2674-8169.2024v6n6p2143-2153
PDF (Português (Brasil))

References

Al Shukri, M. et al. Is there a difference in the clinical profile and outcome of women using levonorgestrel IUD for abnormal uterine bleeding and those using it for contraception?: A comparative cross-sectional study. Turkish Journal of Obstetrics and Gynecology, 21(1): 7-14, 2024.

Costescu, D. et al. Discontinuation rates of intrauterine contraception due to unfavorable bleeding: a systematic review. BMC Women's Health, 22(1): 82, 2022.

Heikinheimo, O., et al. Bleeding pattern and user satisfaction in second consecutive levonorgestrel-releasing intrauterine system users: results of a prospective 5-year study. Human Reproduction, 29(6): 182-1188, 2014.

Kaislasuo, J., et al. Menstrual characteristics and ultrasonographic uterine cavity measurements predict bleeding and pain in nulligravid women using intrauterine contraception. Human Reproduction, 30(7): 1580-1588, 2015.

Luukkainen, T., & Toivonen, J. Levonorgestrel-releasing IUD as a method of contraception with therapeutic properties. Contraception, 52(5): 269-276, 1995.

Minalt, N. et al. Association between intrauterine device use and endometrial, cervical, and ovarian cancer: an expert review. American Journal of Obstetrics and Gynecology, 229(2): 93-100, 2023.

Miranda, L. et al. Continuation Rates of the 52-mg Levonorgestrel-releasing Intrauterine System according to the Primary Reason for its Use. Revista Brasileira de Ginecologia e Obstetrícia, 43(4): 291-296, 2021.

Modesto, W. et al. A randomized clinical trial of the effect of intensive versus non-intensive counselling on discontinuation rates due to bleeding disturbances of three long-acting reversible contraceptives. Human Reproduction, 29(7), 2014.

Papaikonomou, K. et al. Mifepristone treatment prior to insertion of a levonorgestrel releasing intrauterine system for improved bleeding control - a randomized controlled trial. Human Reproduction, 33(11): 2002-2009, 2018.

Al Shukri, M. et al. Is there a difference in the clinical profile and outcome of women using levonorgestrel IUD for abnormal uterine bleeding and those using it for contraception?: A comparative cross-sectional study. Turkish Journal of Obstetrics and Gynecology, 21(1): 7-14, 2024.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2024 Júlia Valena Paiva da Fonseca, Carla Katharina Torres Begot da Rocha, Giulia Fonsceca, Mariana Bressan Pizarro, Luana Lugli, Caroline Topassi, Maria Laura Brum Paes, Iara Moura Rocha, Breno Clarkes Pereira Gonçalves, Julia Heiko Filgueira Otino, Lorena Doretto Oliveira , Celito Francisco Sari Junior

Downloads

Download data is not yet available.